Results 91 to 100 of about 46,059 (265)
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Mixed-Mode Electro Optical Properties of Ge2Sb2Te5
, 2013 In this paper we present ongoing work on a novel alternative mode of operation of phase change materials, specifically Ge2Sb2Te5: mixed-mode electro-optical operation, which offers a new set of potential applications for this ...
Harish Bhaskaran (1357371) +5 more
core
Binary Genetic Encoding for the Synthesis of Mixed-Mode Circuit Topologies [PDF]
, 2012 A binary genetic encoding (BGE) representation for the automatic synthesisof mixed-mode circuit topologies, is introduced. First, the genetic encodingof unity-gain cells (UGCs), such as voltage (VF) and current followers (CF), andvoltage (VM) and current
MIGUEL AURELIO DUARTE VILLASEÑOR +2 more
core
Fracture Mechanics Investigation of Structures with Defects
, 2013 Fracture mechanics plays an important role in the material science, structure design and industrial production due to the failure of materials and structures are paid high attention in human activities.
Li, Yong <1985>
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Numerical analysis of effects of adhesive type and geometry on mixed-mode failure of adhesive joint
, 2016 In the present study, the effects of the adhesive type and geometry (adhesive thickness and scarf angle) on mixed-mode failure of double scarf adhesive joint (DSJ) under uniaxial tensile loading were numerically examined using the finite element ...
Liao LJ(廖丽涓) +2 more
core +1 more source
Finite element analyses of mode I interlaminar delamination in z-fibre reinforced composite laminates. [PDF]
, 2003 This paper presents a detailed numerical study of the mode I interlaminar fracture of carbon/epoxy composite laminates with z-fibre reinforcement. The study was performed using a double cantilever beam configuration.
Marcello Grassi +3 more
core +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source