Results 111 to 120 of about 46,059 (265)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Mixed-mode delamination in layered isotropic and laminated composite beam structures [PDF]

open access: yes, 2017
Completely analytical theories are presented for calculating the total energy release rate (ERR) in a mixed-mode delamination in layered isotropic and laminated composite straight beam structures and for partitioning it into opening mode I and shearing ...
Christopher Harvey (1256223)   +2 more
core  

Use of Commercial Mixed-Mode Stationary Phases and Sorbents in the High-Performance Liquid Chromatography Analysis and Solid-Phase Extraction of Ionized and Hydrophilic Bioactive Compounds

open access: yesMolecules
Mixed-mode high-performance liquid chromatography (HPLC) is increasingly used for the analysis of ionic and highly hydrophilic drugs, which are difficult to separate by conventional single-mode HPLC.
Takeshi Fukushima   +3 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Mode and Context Effects in Measuring Household Assets [PDF]

open access: yes
Differences in answers in Internet and traditional surveys can be due to selection, mode, or context effects. We exploit unique experimental data to analyze mode and context effects controlling for arbitrary selection.
Arthur van Soest, Arie Kapteyn
core  

Investigation of crack growth behaviour under mixed mode loading [PDF]

open access: yes, 2006
The crack growth resistance of different metals under mixed mode (I+II) and biaxial loading was investigated. Fracture pattern depends on the load ratio under different modes and their level.
Покровский, В. В.   +7 more
core  

Mixed-mode partition theories for one-dimensional delamination in laminated composite beams

open access: yes, 2012
Completely analytical theories are presented for the mixed-mode partitioning of one-dimensional delamination in laminated composite beams. The work builds on previous research by the authors on one-dimensional fractures in layered isotropic beams.
Christopher Harvey (1256223)   +1 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

FEM ANALYSIS ON MIXED-MODE FRACTURE OF CSM-GRP

open access: yes, 1986
A FEM analysis for studying mixed-mode fracture problem of chopped strand matglass fibre reinforced polyester laminate is presented.The analysis is formulated on thebasis of8-node quadrilateral isoparametric element.The collapsed triangular quarter ...
Leech CM, 张双寅
core  

LISS panel > Mixed Mode Experiment

open access: yes, 2009
This study is divided into three parts and combines mixed-mode experiments with other experiments that were incorporated in the questionnaires.
De Leeuw, E.D., Hox, J.J.
core   +1 more source

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