Results 81 to 90 of about 3,604,166 (239)

Calculation method for natural vibration frequency of stern cabin in oceanographic research vessel

open access: yesZhongguo Jianchuan Yanjiu, 2017
Vibration prediction for stern cabins is an important part of research into the global vibration of ships. To address the need to improve precision and efficiency, a study is carried out on the proportion of a mixed model and the length of a 3D stern ...
LIU Xi'an, WU Guangming, LI Weijie
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Efficient Estimation of Marker Effects in Plant Breeding

open access: yesG3: Genes, Genomes, Genetics, 2019
The evaluation of prediction machines is an important step for a successful implementation of genomic-enabled selection in plant breeding. Computation time and predictive ability constitute key metrics to determine the methodology utilized for the ...
Alencar Xavier
doaj   +1 more source

Smoothing with Mixed Model Software [PDF]

open access: yes
Smoothing methods that use basis functions with penalization can be formulated as fits in a mixed model framework. One of the major benefits is that software for mixed model analysis can be used for smoothing.
Long Ngo, Matthew P. Wand
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The Influence of Soil Deformability on the Seismic Response of 3D Mixed R/C–Steel Buildings

open access: yesInfrastructures
Following effective seismic codes, common buildings are considered to be made of the same material throughout the story distribution and based on an ideal rigid soil. However, in daily construction practice, there are often cases of buildings formed by a
Paraskevi K. Askouni
doaj   +1 more source

Spatial statistical analysis and selection of genotypes in plant breeding Seleção de genótipos e análise estatística espacial no melhoramento de plantas

open access: yesPesquisa Agropecuária Brasileira, 2005
The objective of this study was to evaluate the efficiency of spatial statistical analysis in the selection of genotypes in a plant breeding program and, particularly, to demonstrate the benefits of the approach when experimental observations are not ...
João Batista Duarte, Roland Vencovsky
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

A Poisson Mixed Model with Nonnormal Random Effect Distribution

open access: yes, 2011
We propose in this paper a random intercept Poisson model in which the random effect distribution is assumed to follow a generalized log-gamma (GLG) distribution.
de Castro, Mario   +2 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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