Results 171 to 180 of about 1,513,668 (313)

Bayesian Nonparametric Estimation and Consistency of Mixed Multinomial Logit Choice Models [PDF]

This paper develops nonparametric estimation for discrete choice models based on the Mixed Multinomial Logit (MMNL) model. It has been shown that MMNL models encompass all discrete choice models derived under the assumption of random utility maximization,
Lancelot F. James, John W. Lau, Pierpaolo De Blasi   +2 more
core  

Deep Mixture of Linear Mixed Models for Complex Longitudinal Data. [PDF]

Stat Med
Kock L, Klein N, Nott DJ.
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Formulating and Solving Exhaustible Resource Models as Mixed Complementarity Problems in GAMS [PDF]

In this paper a formulation of dynamic non-linear programs as mixed complementarity problems (mcp) is shown. Models of exhaustible resource markets are used to describe the transformation.
Sven M. Flakowski
core  

A Bayesian Two-Step Multiple Imputation Approach Based on Mixed Models for Missing EMA Data. [PDF]

Stat Med
Wei Y, Siddique J, Spring B, Hedeker D.
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Bayesian Mixed Models Approach to Exploring Resilience: Impact of Stress on Subjective Health and Affects Over Time During the COVID-19 Pandemic. [PDF]

Int J Methods Psychiatr Res
Schepers M, Schmidtmann I, Schäfer SK, Yilmaz S, Baumkötter R, Hartmann A, Petersen J, Hettich-Damm N, Wild P, Zahn D, Wollschläger D.   +10 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Selecting stable rice mutants with linear mixed models (LMM) and stability indexes. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Sharifi P, Ebadi AA, Hallajian MT, Aminpanah H.   +3 more
europepmc   +1 more source

glmmPen: High Dimensional Penalized Generalized Linear Mixed Models. [PDF]

R J, 2023
Heiling HM, Rashid NU, Li Q, Ibrahim JG.
europepmc   +1 more source