Results 21 to 30 of about 3,902,333 (190)

Age and diet shape the genetic architecture of body weight in diversity outbred mice

open access: yeseLife, 2022
Understanding how genetic variation shapes a complex trait relies on accurately quantifying both the additive genetic and genotype–environment interaction effects in an age-dependent manner. We used a linear mixed model to quantify diet-dependent genetic
Kevin M Wright   +6 more
doaj   +1 more source

Cluster Correlation in Mixed Models [PDF]

open access: yes, 2000
We evaluate the dependence of the cluster correlation length r_c on the mean intercluster separation D_c, for three models with critical matter density, vanishing vacuum energy (Lambda = 0) and COBE normalized: a tilted CDM (tCDM) model (n=0.8) and two ...
A. Gardini   +16 more
core   +2 more sources

Stability and adaptability of curled green-leaf lettuce lines using the REML/Blup mixed model [PDF]

open access: yesPesquisa Agropecuária Brasileira, 2018
: The objective of this work was to estimate the stability and genotypic adaptability of advanced lines and cultivars of curled green-leaf lettuce (Lactuca sativa), in different growing environments and seasons, using the REML/Blup mixed model.
Willame dos Santos Candido   +6 more
doaj   +1 more source

Multiple testing correction in linear mixed models. [PDF]

open access: yes, 2016
BackgroundMultiple hypothesis testing is a major issue in genome-wide association studies (GWAS), which often analyze millions of markers. The permutation test is considered to be the gold standard in multiple testing correction as it accurately takes ...
Eskin, Eleazar   +3 more
core   +2 more sources

Taming Human Genetic Variability: Transcriptomic Meta-Analysis Guides the Experimental Design and Interpretation of iPSC-Based Disease Modeling

open access: yesStem Cell Reports, 2017
Both the promises and pitfalls of the cell reprogramming research platform rest on human genetic variation, making the measurement of its impact one of the most urgent issues in the field.
Pierre-Luc Germain, Giuseppe Testa
doaj   +1 more source

R-environment package for regression analysis [PDF]

open access: yesPesquisa Agropecuária Brasileira, 2018
: The objective of this work was to develop a package in the R environment for automating and facilitating the regression analysis. Named easyreg, the package offers five functions.
Emmanuel Arnhold
doaj   +1 more source

Selection and Estimation for Mixed Graphical Models [PDF]

open access: yes, 2014
We consider the problem of estimating the parameters in a pairwise graphical model in which the distribution of each node, conditioned on the others, may have a different parametric form. In particular, we assume that each node's conditional distribution
Chen, Shizhe   +2 more
core   +3 more sources

The Parisi formula for mixed $p$-spin models [PDF]

open access: yes, 2014
The Parisi formula for the free energy in the Sherrington-Kirkpatrick and mixed $p$-spin models for even $p\geq2$ was proved in the seminal work of Michel Talagrand [Ann. of Math. (2) 163 (2006) 221-263].
Panchenko, Dmitry
core   +3 more sources

Mixed Markov models [PDF]

open access: yesProceedings of the National Academy of Sciences, 2003
Markov random fields can encode complex probabilistic relationships involving multiple variables and admit efficient procedures for probabilistic inference. However, from a knowledge engineering point of view, these models suffer from a serious limitation.
openaire   +3 more sources

Four ways in which data-free papers on animal personality fail to be impactful

open access: yesFrontiers in Ecology and Evolution, 2015
The literature on animal personality is dominated by papers lacking any data. These papers, which we will call ‘data-free’ papers, are cited and recognized twice as much as comparable empirical studies. In this data-free paper, we highlight 4 common data-
Nicholas eDiRienzo   +1 more
doaj   +1 more source

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