Results 151 to 160 of about 11,777,244 (243)

Psychological Stress Promotes Tumor Growth in Hepatocellular Carcinoma Models Through Myeloid Signaling

Cancer Science, EarlyView.
Psychological stress promotes hepatocellular carcinoma progression through coordinated regulation of macrophages and neutrophils. Noradrenaline activates ADRB2 signaling in intratumoral macrophages, leading to CXCL2 production and neutrophil recruitment.
Keita Ogawa, Takahiro Aoki, Tatsuya Kaneko, Hongxuan Wang, Daiki Shimizu, Daisuke Katsumi, Iori Kojima, Hidekazu Tanaka, Kiwamu Motoyoshi, Ko Ozaki, Katsuhiro Nishimura, Tomohisa Iinuma, Mariko Takami, Shinichiro Motohashi   +13 more
wiley   +1 more source

When Small Cells Matter: Diagnosing Bladder Small Cell Carcinoma on Urine Cytology

Cytopathology, EarlyView.
Small cell carcinoma of the bladder is rare, aggressive and diagnostically challenging on urine cytology. We report a case detected in urine and confirmed by cell block immunohistochemistry, highlighting the importance of careful assessment and limitations of the Paris System.
Haley Corbin, Samer Khader, Gabriela Quiroga‐Garza, Liron Pantanowitz   +3 more
wiley   +1 more source

What Are Computer‐Assisted Methods Achieving in Fine‐Needle Aspiration Cytology of the Pancreas? A Systematic Review and Meta‐Analysis

Cytopathology, EarlyView.
This meta‐analysis demonstrates high diagnostic accuracy of computer‐assisted methods in pancreatic EUS‐FNA cytology (AUC 0.92–0.96) and supports an integrated, cytopathologist‐led workflow in which artificial intelligence functions as an adjunct to diagnostic interpretation and on‐site evaluation (ROSE). Created in BioRender. Mohamed Mirzan, A. (2026)
Al‐Amaan Mohamed Mirzan, Roberto Dina
wiley   +1 more source

TROP2 immunoreactivity in pulmonary large cell neuroendocrine carcinoma

Histopathology, EarlyView.
Frequently positive TROP2 IHC suggests that TROP2 antibody‐drug conjugates may be potential treatments for LCNEC. Introduction TROP2 antibody‐drug conjugates have shown promising anti‐tumour activity, but neither the activity of these agents nor TROP2 expression has been well studied in pulmonary large cell neuroendocrine carcinoma (LCNEC), a rare and ...
Michael Minkley, Kashif Ravasia, Thi Nghiem, Dongxia Gao, Jamie Feng, Andrew Churg, Julia R Naso   +6 more
wiley   +1 more source

Merkel cell carcinoma: an updated guide for pathologists

Histopathology, EarlyView.
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma for which the differential diagnosis can include other small cell malignancies (especially metastatic small cell carcinoma) or cutaneous carcinoma. Morphologic and immunophenotypic aberrancies in MCC can increase diagnostic challenge.
Paul W. Harms
wiley   +1 more source

Mixed neuroendocrine-non-neuroendocrine neoplasms (MiNEN) of pancreas: a rare entity-worth to note. [PDF]

BMJ Case Rep, 2020
Varshney B, Bharti JN, Varshney VK, Yadav T.   +3 more
europepmc   +1 more source

Novel and emerging skin carcinomas and adnexal tumours

Histopathology, EarlyView.
The present review aims to provide an overview of the main emerging skin epithelial tumours, with particular emphasis on salivary gland analogue sweat gland tumours and poorly differentiated carcinomas. Epidermal and adnexal tumours of the skin constitute a complex and heterogeneous group of neoplasms, with distinct morphology and behaviour.
Thibault Kervarrec, Maxime Battistella, Nicolas Macagno   +2 more
wiley   +1 more source

Gastric mixed neuroendocrine–non-neuroendocrine neoplasms: Report of two cases

Asian Journal of Surgery
LiLi Qian, Yanling Jin, Meihua Ye
doaj   +1 more source

Mixed neuroendocrine-non-neuroendocrine neoplasms (MiNEN) in the non-ampullary region of the duodenum: a case report. [PDF]

J Surg Case Rep
Matsushita K, Urakami A, Matsubara M, Akagi A, Urano T, Ishida N, Takaoka M, Fujiwara H, Akiyama T, Yamatsuji T.   +9 more
europepmc   +1 more source

Whole‐slide analysis of mitotic activity in melanoma reveals higher‐proliferation hotspots and distinct spatial patterns

Histopathology, EarlyView.
Whole‐slide analysis of melanoma identified higher‐proliferation mitotic hotspots than routine pathology assessment and revealed distinct spatial patterns of mitotic organization, highlighting the potential of computational mitosis mapping to provide insights beyond conventional mitotic counting.
Shlomo Tsuriel, Batel Gabay, Victoria Hannes, Rami R Hagege, Dov Hershkovitz   +4 more
wiley   +1 more source