Challenges in High-grade Neuroendocrine Neoplasms and Mixed Neuroendocrine/Non-neuroendocrine Neoplasms [PDF]
Endocrine Pathology, 2021 AbstractThe growth in knowledge of the pathogenesis, molecular background, and immunohistochemical profile of neuroendocrine neoplasms (NENs) has led not only to an increased awareness of these diseases but also to several changes of the nomenclature.
Stefano la Rosa
exaly +9 more sources
Mixed Neuroendocrine Non-Neuroendocrine Neoplasms of the Gastrointestinal Tract: A Case Series [PDF]
Healthcare (Switzerland), 2022 Mixed neuroendocrine non-neuroendocrine neoplasms (MiNENs) refer to heterogenous rare neoplasms constituted of at least a neuroendocrine population—either well-differentiated, or more frequently poorly differentiated—and a non-neuroendocrine population, both accounting for at least 30% of the whole tumor mass.
Michele Orditura +2 more
exaly +5 more sources
Mixed Neuroendocrine Non-Neuroendocrine Neoplasms: A Systematic Review of a Controversial and Underestimated Diagnosis [PDF]
Journal of Clinical Medicine, 2020 Mixed neuroendocrine non-neuroendocrine neoplasms (MiNENs) represent a rare diagnosis of the gastro-entero-pancreatic tract. Evidence from the current literature regarding their epidemiology, biology, and management is of variable quality and conflicting.
Melissa Frizziero +2 more
exaly +7 more sources
Tumor Microenvironment in Mixed Neuroendocrine Non-Neuroendocrine Neoplasms: Interaction between Tumors and Immune Cells, and Potential Effects of Neuroendocrine Differentiation on the Tumor Microenvironment [PDF]
Cancers, 2022 SIMPLE SUMMARY: The neuroendocrine differentiation of tumors is considered to influence the tumor microenvironment through the secretion of various hormones or growth factors.
Hirofumi Watanabe, Chiaki Sato
exaly +3 more sources
Digestive System Mixed Neuroendocrine-Non-Neuroendocrine Neoplasms [PDF]
Neuroendocrinology, 2017 Mixed neuroendocrine-non-neuroendocrine neoplasms (MiNEN) are a heterogeneous subgroup of rare neoplasms that represent about a third of all poorly differentiated neuroendocrine carcinomas (PDNEC). MiNEN combine a neuroendocrine component, usually a PDNEC, and a non-neuroendocrine component, generally an adenocarcinoma, both accounting for at least 30%
Louis de Mestier +10 more
openaire +3 more sources
Practical hints for the diagnosis of mixed neuroendocrine-non-neuroendocrine neoplasms of the digestive system. [PDF]
World J Gastrointest OncolIn this editorial, a comment on the article by Díaz-López et al published in the recent issue of the 2024 is provided. We focus on the practical implications critical for providing a correct and complete diagnosis of mixed neuroendocrine-non-neuroendocrine neoplasm (MiNEN) in the gastrointestinal system.
Mattiolo P.
europepmc +5 more sources
Mixed neuroendocrine–non-neuroendocrine neoplasm of the ampulla of Vater: a case report
Surgical Case Reports, 2023 Background Mixed neuroendocrine–non-neuroendocrine neoplasms of the ampulla of Vater are rare and heterogenous, making it difficult to achieve a definitive preoperative diagnosis.
Kenjiro Date +8 more
doaj +3 more sources
Recurrent Mixed Neuroendocrine-Non-Neuroendocrine Neoplasm in the Gallbladder: A Case Report [PDF]
Case Reports in Oncology, 2021 Mixed neuroendocrine-non-neuroendocrine neoplasms (MiNEN) of the gallbladder are rare with no established therapeutic strategies. We report a case of recurrent gallbladder MiNEN from a population with a low incidence of gallbladder carcinomas, a review ...
Turki Al-Fayea +4 more
doaj +3 more sources
Clinicopathological Spectrum and Survival in Esophageal Neuroendocrine Carcinoma and Mixed Neuroendocrine-Non-Neuroendocrine Neoplasms: A 74-Patient Cohort [PDF]
Cancer Management and ResearchLingjuan Zhang,1 Shengli Zhou,2 Zhiquan Gong,2 Man Wu,1 Bingxi Zhou,1 Xiuling Li,1 Jian Li,1 Songze Ding1 1Department of Gastroenterology and Hepatology, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, Zhengzhou, People’s ...
Zhang L +7 more
doaj +2 more sources
Mixed Neuroendocrine Non-Neuroendocrine Neoplasm Arising in the Ectopic Gastric Mucosa of Esophagus
Case Reports in Gastroenterology, 2022 Esophageal neuroendocrine neoplasms are extremely rare, and their prognosis is poor. Mixed neuroendocrine non-neuroendocrine neoplasms (MiNENs) are even more rare and are defined as tumors consisting of neuroendocrine carcinoma and either adenocarcinoma ...
Ryosuke Gushima +10 more
doaj +3 more sources