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Pulmonary carcinoid harboring a <i>KRAS</i> G12C mutation identified through comprehensive genomic profiling and responding to sotorasib: A case report. [PDF]
Rare TumorsHamai K +9 more
europepmc +1 more source
A Case of Primary Mixed Neuroendocrine-Non-Neuroendocrine Neoplasms Tumor of the Bladder
Advances in Clinical Medicineopenaire +1 more source
Mixed Neuroendocrine-Non-Neuroendocrine Neoplasms of the Pancreas
Surgical Pathology Clinics, 2022 Pancreatic mixed neuroendocrine-non-neuroendocrine neoplasms (MiNENs) are rare neoplasms, composed of at least two components. The neuroendocrine part is always present. Histology is the most important tool for the diagnosis, but in the case of MiNEN, it is also important for the use of immunohistochemistry, which should include neuroendocrine but also
Claudio Luchini
exaly +4 more sources
Current Treatment Options in Oncology, 2022 OPINION STATEMENT: In the 2019 WHO guidelines, the classification of gastro-entero-pancreatic neuroendocrine neoplasms (GEP NEN) has changed from one being based on Ki-67 proliferation index alone to one that also includes tumor differentiation ...
Ulrich Knigge +2 more
exaly +2 more sources
Neuroendocrine neoplasms of the pancreas: diagnosis and pitfalls
Virchows Archiv Fur Pathologische Anatomie Und Physiologie Und Fur Klinische Medizin, 2021 Common to neuroendocrine neoplasms of the pancreas is their expression of synaptophysin, chromogranin A, and/or INSM1. They differ, however, in their histological differentiation and molecular profile.
Atsuko Kasajima, Gunter Klöppel
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Pathology Research and Practice, 2023 In 2019, the World Health Organization (WHO) classification system updated the definition of mixed neuroendocrine non-neuroendocrine neoplasms (MiNENs), previously known as mixed adenoneuroendocrine carcinomas (MANECs). The clinicopathological characteristics of this new definition remains to be clarified.We analyzed the clinical data of 43 patients ...
Rong Lin, Huiying Shi
exaly +3 more sources
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Presentation and outcome of mixed neuroendocrine non-neuroendocrine neoplasms of the pancreas
Pancreatology, 2021Mixed neuroendocrine non-neuroendocrine neoplasms (MiNEN) of the pancreas and periampullary region are extremely rare and heterogeneous malignancies. Literature is sparse, clinical management is not standardized and little is known about survival outcomes.
Oliver Strobel +2 more
exaly +3 more sources
Mixed neuroendocrine non-neuroendocrine neoplasm: a case report and review
Clinical Journal of Gastroenterology, 2021Mixed neuroendocrine non-neuroendocrine neoplasm (MiNEN) of the pancreas is a rare entity, and obtaining a preoperative diagnosis is difficult. We present a 70-year-old man in whom the possibility of MiNEN was successfully discovered preoperatively by endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA).
Sawako Hiroi +8 more
openaire +2 more sources
An Update on the Management of Mixed Neuroendocrine-Non-neuroendocrine Neoplasms (MiNEN)
Current Treatment Options in Oncology, 2022The classification of mixed neuroendocrine-non-neuroendocrine neoplasms (MiNEN) is evolving, and no clear management guidelines are currently available. However, recent studies provide insight into factors affecting outcomes and could help develop treatment decisions for patients with these rare malignancies.
Aasems Jacob +4 more
openaire +2 more sources
Endocrine Pathology, 2016 The wide application of immunohistochemistry to the study of tumors has led to the recognition that epithelial neoplasms composed of both a neuroendocrine and nonneuroendocrine component are not as rare as traditionally believed.
Silvia Uccella +2 more
exaly +2 more sources