Results 31 to 40 of about 4,779 (264)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
A Multilinear Mixing Model for Nonlinear Spectral Unmixing [PDF]
IEEE Transactions on Geoscience and Remote Sensing, 2016 In hyperspectral unmixing, bilinear and linear–quadratic models have become popular recently, and also the polynomial postnonlinear model shows promising results. These models do not consider endmember interactions involving more than two endmembers, although such interactions might compose a nontrivial part of the observed spectrum in scenarios ...
Rob Heylen, Paul Scheunders
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Discrete Dynamics in Nature and Society, 2012 Using generalized variational principle and Riccati technique, new oscillation criteria are established for forced second-order differential equation with mixed nonlinearities, which improve and generalize some recent papers in the literature.
Jing Shao, Fanwei Meng, Xinqin Pang
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Lyapunov-type inequalities for certain higher-order difference equations with mixed non-linearities
Advances in Difference Equations, 2018 In this paper, we establish some new Lyapunov-type inequalities for some higher-order difference equations with boundary conditions. The obtained inequalities generalize the existing results in the literature.
Haidong Liu
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Towards a Proof of Bahri–Coron’s Type Theorem for Mixed Boundary Value Problems
Mathematics, 2023 We consider a nonlinear variational elliptic problem with critical nonlinearity on a bounded domain of Rn,n≥3 and mixed Dirichlet–Neumann boundary conditions.
Azeb Alghanemi +3 more
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FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Frontiers in Sustainability, 2022 Heat Exchanger Network (HEN) synthesis is primarily formulated as a mixed integer non-linear programming (MINLP) problem based on method of stage-wise superstructure (SWS).
Zekun Yang, Nan Zhang, Robin Smith
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FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
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Advances in Difference Equations, 2019 This paper investigates a class of nonlinear dynamic integral inequalities with mixed nonlinearities in two independent variables. The obtained results can be utilized to study the boundedness of partial dynamic systems on time scales.
Min Fan, Yazhou Tian, Fanwei Meng
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