Results 41 to 50 of about 4,779 (264)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Picone-type inequality and Sturmian comparison theorems for quasilinear elliptic operators with p(x)-Laplacians

Electronic Journal of Differential Equations, 2012
A Picone-type inequality for quasilinear elliptic operators with mixed nonlinearities and with p(x)-Laplacian is established, and Sturmian comparison theorems are derived on the basis of the Picone-type inequality.
Norio Yoshida
doaj  

Darboux transformation and dark vector soliton solutions for complex mKdV systems

Partial Differential Equations in Applied Mathematics, 2021
A Darboux transformation and general vector dark soliton solutions are constructed for multi-component complex modified Korteweg–de Vries (mKdV) system.
Rusuo Ye, Yi Zhang, Wen-Xiu Ma
doaj   +1 more source

Nonlinear Diffusion Model for Rayleigh-Taylor Mixing [PDF]

Physical Review Letters, 2010
4 pages, 4 figure, PRL in ...
Boffetta, G., De Lillo, F., Musacchio, S.   +2 more
openaire   +3 more sources

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Normalized solutions for planar Schrödinger–Poisson equation with mixed nonlinearities

Bulletin of Mathematical Sciences
This paper deals with the following Schrödinger–Poisson equation with mixed nonlinearities: −Δu+λu+12π(ln|⋅|∗|u|2)u=μ|u|q−2u+|u|p−2u,x∈ℝ2,∫ℝ2u2dx=c, where [Formula: see text], [Formula: see text], [Formula: see text], [Formula: see text] is a given real ...
Muhua Shu, Lixi Wen, Heng Yang
doaj   +1 more source

Mixed Nonlinear Response and Transition of Nonlinearity in a Piezoelectric Membrane

ACS Applied Electronic Materials
Nonlinearities play a critical role in the dynamics of mechanical resonators, enhancing sensitivity and enabling signal manipulation. Understanding the parameters affecting nonlinearities is crucial for developing strategies to counteract their effects or manipulate them for improved device performance. This study investigates the impact of fabrication-
Nishta Arora, Priyanka Singh, Randhir Kumar, Rudra Pratap, Akshay Naik   +4 more
openaire   +4 more sources

A Mixed Algorithm for Nonlinear Complementarity Problems

Journal of Computers, 2011
Combining nonmonotone trust region algorithms and PSO methods, we propose a mixed method for nonlinear complementarity problems. The iterative formula of μ k is very simple. When the determinant of  B k +λ k I is very large or small, the PSO method will obtain a new point which gets us better astringency.
Xi-yun Wang, Ya Wang, Yu-Yang Wang
openaire   +1 more source

Planar Solid‐State Nanopores Toward Scalable Nanofluidic Integration Based on CMOS Technology

Advanced Engineering Materials, EarlyView.
We present a scalable silicon‐based fabrication strategy for planar solid‐state nanopores to enable their integration with complex nanofluidic systems. Prototype devices demonstrate normal voltage‐current characteristics, good noise performance, and appreciable streaming currents. Our CMOS‐compatible fabrication process offers precise geometric control
Ngan Hoang Pham, Chenyu Wen, Mohammad Hadi Khaksaran, Won‐Yong Lee, Javier Cruz, Klas Hjort, Dongping Wu, Shi‐Li Zhang   +7 more
wiley   +1 more source