Results 71 to 80 of about 89,529 (298)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Cloud component removal for shallow water depth retrieval with multi-spectral satellite imagery

open access: yesTerrestrial, Atmospheric and Oceanic Sciences, 2019
Water depth and the topography under water provide important information for near shore human activities. With the intensification of international territory concerns, bathymetric mapping is also gaining attention.
Po-Yao Tsou   +2 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Improving Land Use/Land Cover Classification by Integrating Pixel Unmixing and Decision Tree Methods

open access: yesRemote Sensing, 2017
Decision tree classification is one of the most efficient methods for obtaining land use/land cover (LULC) information from remotely sensed imageries. However, traditional decision tree classification methods cannot effectively eliminate the influence of
Chao Yang   +5 more
doaj   +1 more source

A Physics-Based Unmixing Method to Estimate Subpixel Temperatures on Mixed Pixels

open access: yes, 2015
International audienceThis paper presents a new algorithm for the analysis of linear spectral mixtures in the thermal infrared domain, with the goal to jointly estimate the abundance and the subpixel temperature in a mixed pixel, i.e., to estimate the ...
Shimoni, M.   +4 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Decomposition of mixed pixels in remote sensing images to improve the area estimation of agricultural fields [PDF]

open access: yes, 1998
Contains fulltext : 18654.pdf (Publisher’s version ) (Open Access)For the European Union it is of great importance to be able to estimate the area of an agricultural field in order to manage its agricultural subsidy system.
klein Gebbinck, M.S.
core  

Seamless bare-hand interaction in mixed reality

open access: yes, 2018
Unrealistic Mixed Reality (MR) experiences can be caused by unprocessed occlusions between real and augmented objects during interactions. Depth knowledge is indeed key to achieve a seamless visualisation when a bare hand interacts with an augmented ...
Fabio Poiesi   +5 more
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Hybrid Constraints of Pure and Mixed Pixels for Soft-Then-Hard Super-Resolution Mapping with Multiple Shifted Images

open access: yes, 2015
Multiple shifted images (MSIs) have been widely applied to many super-resolution mapping (SRM) approaches to improve the accuracy of fine-scale land-cover maps.
Heuvelink, G.B.M.   +9 more
core   +2 more sources

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