Results 31 to 40 of about 232,906 (264)
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
“I Am The New America”: Representing and Negotiating American Families in Mixed Race Memoirs
This article provides an analysis of two mixed race memoirs from the 1990s/ 2000s. It looks at the establishment of mixed race families and mixed race history by these texts and contextualizes them in the larger process of the American nation coming to ...
Julia Sattler
doaj +1 more source
Race/ethnicity differences in risk and protective factors for marijuana use among U.S. adolescents
Background Little is known about how race and ethnicity influence marijuana-specific risk and protective factors in U.S. adolescents. We examined differences in risk and protective factors of marijuana use (MU) and their associations with MU by race ...
Meen Hye Lee +2 more
doaj +1 more source
In the end of the 19th century, the Recueil Dareste and the Recueil Penant are a part of main French periodicals specialized in colonial law. Through a complete perusal of these two reviews, this contribution aims at realizing a thematic and comparative ...
Silvia Falconieri
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Race and Mortality in Hemodialysis Patients in BrazilPlain-Language Summary
Rationale & Objective: Studies in the United States and United Kingdom generally report better survival for Black than White patients undergoing maintenance hemodialysis, a finding not explained by differences in sociodemographics or comorbid ...
Marcelo Barreto Lopes +9 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Multiplicity within Singularity: Racial Categorization and Recognizing “Mixed Race” in Singapore
“Race” and racial categories play a significant role in everyday life and state organization in Singapore. While multiplicity and diversity are important characteristics of Singaporean society, Singapore's multiracial ideology is firmly based on separate,
Zarine L. Rocha
doaj +2 more sources

