Results 41 to 50 of about 398,615 (297)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Integrating IoT Modern Communication Architectures into the New Generation of VR/MR Environments [PDF]

Annals of Dunarea de Jos University. Fascicle I : Economics and Applied Informatics, 2019
This paper presents how modern IoT communication architectures can be successfully used in building both virtual and mixed reality scenarios. The IoT architecture enables the use of LPWAN technologies with a limited Maximum Transmission Unit for an ...
Dragos Sebastian CRISTEA, Ruben Cantarero NAVARRO, Javier Sánchez RIQUELME, Marius IVANOV, Muneeb ANWAR, George SUCIU   +5 more
doaj  

Integrating evolution into ecological modelling: accommodating phenotypic changes in agent based models. [PDF]

, 2013
PMCID: PMC3733718This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited ...
A Grafen, A Grafen, AA Hoffmann, AJ van Noordwijk, Aristides Moustakas, B Matthews, BEC Lyon, C Both, C Parmesan, C Zheng, CM Perrins, D Eisinger, G-R Walther, HQP Crick, JE Brommer, JMJ Travis, JR Bridle, JS Clark, Jérémie Bourdon, K Schiffers, LR Lawlor, M Begon, Matthew R. Evans, ME Visser, MJ Mustard, MR Evans, MR Evans, MT Ghiselin, NG Hairston, P Medawar, PA Abrams, PR Moorcroft, R Lande, RAG-C Stillman, RH McCleery, S Descamps, S Verhulst, SP Ellner, SW Pacala, T Coulson, T Coulson, T Day, TG Benton, THG Ezard, TJ Givnish, V Grimm, WJ Sutherland, WJ Sutherland, YG Matsinos   +48 more
core   +3 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Practical Application of Augmented/Mixed Reality Technologies in Surgery of Abdominal Cancer Patients

Journal of Imaging, 2022
The technology of augmented and mixed reality (AR/MR) is useful in various areas of modern surgery. We considered the use of augmented and mixed reality technologies as a method of preoperative planning and intraoperative navigation in abdominal cancer ...
Vladimir M. Ivanov, Anton M. Krivtsov, Sergey V. Strelkov, Anton Yu. Smirnov, Roman Yu. Shipov, Vladimir G. Grebenkov, Valery N. Rumyantsev, Igor S. Gheleznyak, Dmitry A. Surov, Michail S. Korzhuk, Valery S. Koskin   +10 more
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Mixed-Reality Based Multi-Agent Robotics Framework for Artificial Swarm Intelligence Experiments

IEEE Access, 2023
The term “Swarm intelligence” outlines a broad scope, which is generally defined as the collective behaviour of many individuals towards a certain task, each operating autonomously in a decentralised manner.
Dilshani Karunarathna, Nuwan Jaliyagoda, Ganindu Jayalath, Janaka Alawatugoda, Roshan Ragel, Isuru Nawinne   +5 more
doaj   +1 more source

Nachhaltigkeit als Politische Ökologie : Eine Kontroverse über Natur, Technik und Umweltpolitik. [PDF]

, 2010
Mixed Reality (MR) is a technique to blend together the real life with virtual reality. Using this technique it is, for instance, possible for experts to assist persons several miles away to perform tasks by talking and  visually aid them. In this thesis
Behrend, Hanna, Döge, Peter
core  

Occlusion Handling using Semantic Segmentation and Visibility-Based Rendering for Mixed Reality

, 2017
Real-time occlusion handling is a major problem in outdoor mixed reality system because it requires great computational cost mainly due to the complexity of the scene.
Fukiage, Taiki, Hori, Tomoki, Oishi, Takeshi, Okamoto, Yasuhide, Roxas, Menandro   +4 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source