Results 91 to 100 of about 7,094,748 (296)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Mixed mycorrhizal strategies and environmental pressures synergistically regulate diversity-soil total organic carbon relationships in temperate forests

open access: yesEcological Indicators
Understanding how mycorrhizal strategies mediate forest diversity-carbon storage relationships under environmental stress remains a critical knowledge gap for predicting ecosystem responses to global change.
Bo Jia   +6 more
doaj   +1 more source

Three point shooting and efficient mixed strategies: A portfolio management approach

open access: yesJournal of Sports Analytics, 2018
Using mean/variance investment theory, we identify the efficient mixed shot type strategy for National Basketball Association (NBA) teams. The proportion of 3-point shots in this mixed strategy closely tracks risk and the change in expected points from ...
Mark Fichman, John O’Brien
doaj   +1 more source

Intention to stay and associated factors among nurses working in selected public hospitals of the South Ethiopian region: A mixed-method study [PDF]

open access: yesJournal of Nursing Advances in Clinical Sciences
Retaining nurses is a worldwide issue, especially in developing nations, impacting the quality of healthcare services and the overall nursing workforce. This study aimed to assess the intention to stay in the nursing profession and its determinants among
Getachew Gelto   +5 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Mixed strategies in baseball, dating and paying your taxes [Game theory]

open access: yes, 2014
Educação Superior::Ciências Exatas e da Terra::Ciência da ComputaçãoPresents a class about game theory. In this lecture is presented three different interpretations of mixed strategies in various contexts: sport, anti-terrorism strategy, dating, paying ...
Polak, Ben
core  

Not all coping strategies are created equal: a mixed methods study exploring physicians' self reported coping strategies

open access: yesBMC Health Services Research, 2010
Background Physicians experience workplace stress and draw on different coping strategies. The primary goal of this paper is to use interview data to explore physicians' self reported coping strategies.
Wallace Jean E, Lemaire Jane B
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

The evolution of mixed strategies in population games [PDF]

open access: yes, 2008
We study the evolution of mixed strategies in population games. At any time, the distribution of mixed strategies over agents in a population is described by a density function. A pair of players is chosen randomly in each round of the game. After each
Lahkar, R., Seymour, R.
core  

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