Results 131 to 140 of about 5,986,962 (301)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Taita Taveta County Fiscal Strategy Paper 2014
, 2014 The 2014 County Fiscal Strategy Paper is the first of its kind under the devolved system of Governance in Taita Taveta County, which aims at ensuring an effective linkage between policies, planning and budgeting.
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Mixed strategies in baseball, dating and paying your taxes [Game theory]
, 2016 Educação Superior::Ciências Exatas e da Terra::Ciência da ComputaçãoPresents a class about game theory. In this lecture is presented three different interpretations of mixed strategies in various contexts: sport, anti-terrorism strategy, dating, paying ...
Polak, Ben
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
National Wildlife Strategy 2018-2030
, 2018 Kenya ranks highly as one of the biodiversity rich country’s in the World. The iconic wildlife and the diverse conservation areas are among the countries most valuable assets.
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Kenya Health Sector Referral Strategy 2014-2018
, 2014 The overall goal of the Kenya Health Sector Referral Strategy is to improve client access to referral. The objectives of the strategy are to realise improved capacity of health providers to identify clients who require referral, develop protocols that ...
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Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Finite Population Dynamics and Mixed Equilibria [PDF]
This paper examines the stability of mixed-strategy Nash equilibria of sym- metric games, viewed as population profiles in dynamical systems with learning within a single, finite population.
Carlos Alós-Ferrer
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