The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
Electrical impedance tomography-guided individualized ventilation strategy in patients with trauma-related and postoperative acute respiratory distress syndrome. [PDF]
Nguyen Viet M +4 more
europepmc +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
Clinical Outcomes and Factors Associated with MACCE in Chinese Patients Undergoing Single-Hospitalization PCI and Transfemoral TAVR. [PDF]
Tan T, Awakeri A, Cui H, Zhu E, Lai Y.
europepmc +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
AGV navigation in complex environments: A cooperative trajectory optimization strategy based on SMF-MPC. [PDF]
Ding Z +5 more
europepmc +1 more source
Robust Inference With Ghostknockoffs in Genome-Wide Association Studies With Sample Relatedness. [PDF]
Qi X +5 more
europepmc +1 more source
Growth and nutritional outcomes in children during the first year of cancer treatment: a scoping review with implications for child health care in low- and middle-income countries (LMICs). [PDF]
Manimohan S +2 more
europepmc +1 more source
Does changing clinicians' attitudes toward self-harm reduce coercive interventions in mental health inpatient settings? A quasi-experimental study of staff training. [PDF]
Høst Poulsen K +4 more
europepmc +1 more source
Hybrid Prosthetic and Biological Reconstruction Using Extracorporeal Radiotherapy for Long-Segment Humeral Osteosarcoma: A Case Report. [PDF]
Kantiwal P +5 more
europepmc +1 more source

