Time aware cyclic queuing forwarding traffic scheduling algorithm considering reallocation and priority sorting (RPS-TACQF). [PDF]
Sci RepShen Y, Chen X, Ma X.
europepmc +1 more source
A Drug‐Gated, Modular STAb‐T Immunotherapy With External Control
Advanced Science, EarlyView.Engineered STAb‐TON cells act as programmable living factories that continuously secrete inactive antibody modules, which assemble extracellularly into a functional T cell engager only upon small‐molecule administration. This externally controlled platform enables reversible, on‐demand regulation of antitumor immunity, establishing a new paradigm for ...
Susana Luengo‐Arias +23 more
wiley +1 more source
Multiscale Traffic Dynamics Representation for Forecasting via MEMD-Guided Dual-Branch Recurrent Networks. [PDF]
Sensors (Basel)Qian Y +5 more
europepmc +1 more source
TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis
Advanced Science, EarlyView.A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu +12 more
wiley +1 more source
Assessment of pedestrian safety margins at unsignalized mid block crossings in Patna. [PDF]
Sci RepSuman NK, Mondal S, Lokesh AK.
europepmc +1 more source
OsCPK12‐OsATPD1 Module Regulates Photosynthetic Acclimation to Light Stress in Rice
Advanced Science, EarlyView.OsCPK12 interacts and phosphorylates OsAtpD1 at Ser8 in its transit peptide. This phosphorylation promote its chloroplast translocation, thereby maintaining ATP synthase activity and proton gradient (ΔpH) homeostasis and regulating photosynthetic acclimation, photoprotection, and repair under light stress.
Beifang Wang +17 more
wiley +1 more source
Research on optimization of train routing problem for railway hubs considering passenger demand. [PDF]
PLoS OneWang Y.
europepmc +1 more source
Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants
Advanced Science, EarlyView.Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer +17 more
wiley +1 more source
Reproducible floating car data monitoring for data-scarce highway corridors: A TomTom-HERE benchmark study. [PDF]
PLoS OneSun W, Mokhtar SB, Li R, Zou Z.
europepmc +1 more source
Advanced Science, EarlyView.Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang +12 more
wiley +1 more source