Results 61 to 70 of about 5,618,328 (298)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Effect of Connected and Automated Vehicles on Disturbance Suppression in Mixed Traffic Flow: Spatial Distribution and Stability

Elektronika ir Elektrotechnika
With the progressive integration of connected and automated vehicles (CAVs) into existing transportation systems, the characteristics of mixed traffic flow comprising CAVs and human‐driven vehicles (HDVs) undergo a profound transformation.
Yuelei Zhang, Feng Yue, Rui Zhang
doaj   +1 more source

A Traffic Flow Evolution Process toward Mixed Equilibrium with Multicriteria of Route Choice Behaviour

Journal of Advanced Transportation, 2020
Based on the price-quantity adjustment behaviour principle of disequilibrium theory, the route choices of travellers are also affected by a quantity signal known as traffic flow, while the route cost is considered as a price signal in economics ...
Xiangjun Jiang, Zhongxiang Huang, Zhenyu Zhao   +2 more
doaj   +1 more source

Comparing traffic state estimators for mixed human and automated traffic flows [PDF]

Transportation Research Part C: Emerging Technologies, 2017
Abstract This article addresses the problem of modeling and estimating traffic streams with mixed human operated and automated vehicles. A connection between the generalized Aw Rascle Zhang model and two class traffic flow motivates the choice to model mixed traffic streams with a second order traffic flow model.
Ren Wang, Yanning Li, Daniel B. Work
openaire   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

An Anisotropic Traffic Flow Model with Look-Ahead Effect for Mixed Autonomy Traffic

Transportation Research Record: Journal of the Transportation Research Board
In this paper we extend the Aw–Rascle–Zhang (ARZ) non-equilibrium traffic flow model to take into account the look-ahead capability of connected and autonomous vehicles (CAVs), and the mixed flow dynamics of human-driven and autonomous vehicles. The look-ahead effect of CAVs is captured by a non-local averaged density within a certain distance (the ...
Shouwei Hui, Michael Zhang
openaire   +2 more sources

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

Internet Traffic Flow Analysis using Hadoop [PDF]

, 2017
The internet traffic analysis elucidates the network administrator for monitoring the ongoing operation in the network and to understand the network so that the behavior could be examined and large problem can be examined.
Sudipa Biswas
core  

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno, Matteo Conti, Ettore Dolcetti, Federica Azzolini, Angela Borrelli, Roberta Fantozzi, Mario Stampanoni Bassi, Giovanni Galifi, Giuseppe Maccarrone, Luca Montaguti, Marco Cervigni, Maddalena Dal Pozzo, Roberto Furlan, Annamaria Finardi, Girolama Alessandra Marfia, Marco Salvetti, Antonella Conte, Fabio Buttari, Diego Centonze, Luana Gilio   +19 more
wiley   +1 more source