Results 81 to 90 of about 9,830,689 (286)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
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Nonoscillation for Functional Differential Equations of Mixed Type
Journal of Mathematical Analysis and Applications, 2000 It is considered the linear autonomous functional-differential equation \[ \dot x(t)+ \int^1_{-1} (d\mu(s)) x(t+ s)= 0 \] which is of mixed (retarted/advanced) type. An example shows that such equations may be nonoscillatory in spite of the existence of the real roots of the characteristic equation.
openaire +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
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A Mixed Problem for One 3D Space Analogue of Hyperbolic Type Equation
Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2010 It is well known that differential equations with an operator are used for study of the processes connected with appearances of vibration and other mechanics problems, and also play an essential role in the theory of approximation and mapping.
M. V. Dolgopolov, I. N. Rodionova
doaj +3 more sources
Tricomi type problem for mixed type equation with sub-diffusion and wave equation [PDF]
, 2019 In this paper, we have considered a Tricomi type problem for mixed type equation with Hilfer’s double order derivative sub-diffusion equation and classical wave equation in a composite domain.
Karimov, E., Kerbal, S.
core
Stability for Functional Equation of Mixed Type in Non-Archimedean Normed Spaces
Journal of Function Spaces, 2014 We take into account the stability of the following functional equation f(x+ay)+f(x-ay)-2f(x)-a2f(y)-a2f(-y)=0 in non-Archimedean normed spaces.
Ick-Soon Chang, Yang-Hi Lee
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Mixed problem for the singular partial differential equation of parabolic type
Karpatsʹkì Matematičnì Publìkacìï, 2018 The scheme for solving of a mixed problem is proposed for a differential equation \[a(x)\frac{\partial T}{\partial \tau}= \frac{\partial}{\partial x} \left(c(x)\frac{\partial T}{\partial x}\right) -g(x)\, T\] with coefficients $a(x)$, $g(x)$ that are the
O.V. Makhnei
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Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source