Results 91 to 100 of about 301,664 (295)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Continuous Production of Docetaxel-Loaded Nanostructured Lipid Carriers Using a Coaxial Turbulent Jet Mixer with Heating System

open access: yesMolecules
The continuous synthesis of nanoparticles (NPs) has been actively studied due to its great potential to produce NPs with reproducible and controllable physicochemical properties.
Hyeon Su Lim, Won Il Choi, Jong-Min Lim
doaj   +1 more source

Loop flow section conditions of the mixable feed in tilted single-screw batch mixer

open access: yesAdvanced Engineering Research, 2016
A mathematical model of the feed mixing in a tilted single-screw circulating batch mixer is presented. The model includes a system of equations of control component concentration change in the representative zones of the mixer. The feed material state at
Victor F. Khlystunov   +3 more
doaj   +1 more source

Pulsed phase locked loop strain monitor [PDF]

open access: yes, 1982
The RF output of a voltage controlled oscillator (VCO) is periodically gated to a transducer which produces acoustic waves in a bolt. The reflected acoustic waves are converted to electrical signals by the transducer and gated to a mixer which also ...
Heyman, J. S.
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Turbofan forced mixer lobe flow modeling. Part 3: Application to augment engines [PDF]

open access: yes
Military engines frequently need large quantities of thrust for short periods of time. The addition of an augmentor can provide such thrust increases but with a penalty of increased duct length and engine weight.
Barber, T., Blatt, J. R., Moore, G. C.
core   +1 more source

Finding the optimal design of a passive microfluidic mixer. [PDF]

open access: yes, 2019
The ability to thoroughly mix two fluids is a fundamental need in microfluidics. While a variety of different microfluidic mixers have been designed by researchers, it remains unknown which (if any) of these mixers are optimal (that is, which designs ...
Brisk, Philip   +5 more
core   +1 more source

Rotor-stator Mixers

open access: yesChemical Engineering Transactions, 2011
Abstract preview not available - see full-text PDF article.
Thomas Rodgers   +4 more
openaire   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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