Results 81 to 90 of about 1,142,402 (245)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Wave propagation, phase mixing and dissipation in Hall MHD [PDF]

open access: yes, 2012
In this thesis the effect of the Hall term in the generalised Ohm’s law on Alfvén (shear) and fast wave propagation and dissipation in the ion cyclotron frequency range is investigated.
Threlfall, James W.
core   +2 more sources

Phytoplankton Biomass Dynamics in the Strait of Malacca within the Period of the SeaWiFS Full Mission: Seasonal Cycles, Interannual Variations and Decadal-Scale Trends

open access: yesRemote Sensing, 2014
Seasonal cycles, interannual variations and decadal trends of Sea-viewing Wide Field-of-view Sensor (SeaWiFS)-retrieved chlorophyll-a concentration (Chl-a) in the Strait of Malacca (SM) were investigated with reconstructed, cloud-free SeaWiFS Chl-a ...
Eko Siswanto, Katsuhisa Tanaka
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Computational science of turbulent mixing and combustion [PDF]

open access: yes, 2010
Implicit Large Eddy Simulation (ILES) with high-resolution and high-order computational modelling has been applied to flows with turbulent mixing and combustion.
Shimada, Yosuke
core   +3 more sources

Neutrality Versus Materiality: A Thermodynamic Theory of Neutral Surfaces

open access: yesFluids, 2016
In this paper, a theory for constructing quasi-neutral density variables γ directly in thermodynamic space is formulated, which is based on minimising the absolute value of a purely thermodynamic quantity J n .
Rémi Tailleux
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Determination of mixing quality in biogas plant digesters using tracer tests and computational fluid dynamics

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2013
The total electricity demand of investigated biogas plants (BGP) makes up 7–8 % of the total electricity produced. Nearly 40 % of this energy is consumed just for mixing in digesters and the energy demand for mixing in some biogas plants can be even ...
Luděk Kamarád   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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