Results 41 to 50 of about 564,502 (238)

Physical modification of concrete mix and concrete

open access: yesIOP Conference Series: Materials Science and Engineering, 2020
Abstract Numerous studies have established that the physicomechanical properties of concrete, in addition to cement activity, type of aggregates, etc., are determined by the V/C value of the concrete mixture [1, 2, 3, 4, 5, 6, 7, 8, 9, 10].
T. Mirzaev   +3 more
openaire   +2 more sources

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

open access: yesMolecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien   +7 more
wiley   +1 more source

Neutrino Physics: Open Theoretical Questions

open access: yes, 2003
We know that neutrino mass and mixing provide a window to physics beyond the Standard Model. Now this window is open, at least partly. And the questions are: what do we see, which kind of new physics, and how far "beyond"?
A. Y. SMIRNOV   +8 more
core   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Anti-counterfeiting: Mixing the Physical and the Digital World [PDF]

open access: yes, 2010
In this paper, we overview a set of desiderata for building digital anti-counterfeiting technologies that rely upon the difficulty of manufacturing randomized complex 3D objects. Then, we observe how this set is addressed by RF-DNA, an anti-counterfeiting technology recently proposed by DeJean and Kirovski.
openaire   +4 more sources

Mixed action simulations: approaching physical quark masses [PDF]

open access: yesProceedings of The XXV International Symposium on Lattice Field Theory — PoS(LATTICE 2007), 2008
Some algorithmic details of our $N_f=2+1$ QCD mixed action simulations with overlap valence and improved Wilson sea quarks are presented.
Z. Fodor   +11 more
openaire   +6 more sources

CP Violation in $D^0-\overline{D^0}$Mixing

open access: yes, 1995
The existence of $D^0-\overline{D^0}$ mixing at a detectable level requires new physics, which effectively yields a $\Delta c = 2$ superweak interaction. In general this interaction may involve significant CP violation.
H. Georgi   +8 more
core   +1 more source

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