Results 51 to 60 of about 564,502 (238)

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Mixed agonist‐antagonist opiates and physical dependence. [PDF]

open access: yesBritish Journal of Clinical Pharmacology, 1979
1 General methods (chronic, subacute and acute) for assessing physical dependence potential, abstinence precipitating capacity and abstinence preventing activity are briefly presented. 2 Direct dependence experiments indicate that, in general, mixed agonist‐antagonist analgesics have relatively lower physical dependence potentials than pure agonist ...
J. J. C. Jacob   +2 more
openaire   +2 more sources

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

The electroweak sphaleron at physical mixing angle

open access: yesPhysics Letters B, 1991
Abstract The electroweak sphaleron, known previously only in the spherical approximation at vanishing mixing, angle, is constructed for the physical value of the mixing angle sin2 θw=0.23. It is symmetric under rotations around the z-axis and parity reflections. Its energy density and total energy differ little from those of the spherical sphaleron.
Burkhard Kleihaus   +3 more
openaire   +2 more sources

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

open access: yesFEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel   +3 more
wiley   +1 more source

Investigation of the Uniformity of Gel Shrinkage by Imaging Tracer Particles Using X‐Ray Microtomography

open access: yesAdvanced Engineering Materials, EarlyView., 2023
A novel method for tracking structural changes in gels using widely accessible microcomputed tomography is presented and validated for various hydro‐, alco‐, and aerogels. The core idea of the method is to track positions of micrometer‐sized tracer particles entrapped in the gel and relate them to the density of the gel network.
Anja Hajnal   +3 more
wiley   +1 more source

Probing New Physics in Rare Charm Processes [PDF]

open access: yes, 1994
The possibility of using the charm system to search for new physics is addressed. Phenomena such as $D^0-\bar D^0$ mixing and rare decays of charmed mesons are first examined in the Standard Model to test our present understanding and to serve as ...
Hewett, J. L.
core   +3 more sources

An approach for coherent periodogram averaging of tilt‐series data for improved contrast transfer function estimation

open access: yesFEBS Open Bio, EarlyView.
The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley   +1 more source

The physics and the mixed Hodge structure of Feynman integrals [PDF]

open access: yes, 2014
This expository text is an invitation to the relation between quantum field theory Feynman integrals and periods. We first describe the relation between the Feynman parametrization of loop amplitudes and world-line methods, by explaining that the first Symanzik polynomial is the determinant of the period matrix of the graph, and the second Symanzik ...
openaire   +4 more sources

Profiling the effect of low frequency mechanical vibration on the metabolic and oxidative stress responses of A431 carcinoma

open access: yesFEBS Open Bio, EarlyView.
20 Hz mechanical vibration induced A431 cancer cells' apoptosis without such effect on other healthy cell lines of L929 and C2C12. Lowered glucose consumption is observed specifically in A431. The expressions of ROS, HMGB1, and HSP1 levels initially increase and subsequently decrease in the cancer cell line, as opposed to L929 and C2C12, which ...
Wresti L. Anggayasti   +5 more
wiley   +1 more source

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