Results 81 to 90 of about 603,220 (270)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Multi-physics Analysis Method and Conceptual Design of Helically Metallic Fuel
Yuanzineng kexue jishuThe helically metallic fuel is promising to improve the power density and safety margin of reactors core by its advantages of high thermal conductivity, large heat transfer area-to-volume ratio and continual inter-channel mixing.
GU Hanyang, XIAO Yao, CONG Tenglong, GUO Hui, FU Junsen, CAI Mengke, SONG Qufei
doaj +1 more source
Influence of Turbulent Scalar Mixing Physics on Premixed Flame Propagation
Journal of Combustion, 2011 The influence of reactive scalar mixing physics on turbulent premixed flame propagation is studied, within the framework of turbulent flame speed modelling, by comparing predictive ability of two algebraic flame speed models: one that ...
H. Kolla, N. Swaminathan
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
An Appraisal of Muon Neutrino Disappearance at Short Baseline
Advances in High Energy Physics, 2013 Neutrino physics is nowadays receiving more and more attention as a possible source of information for the long-standing problem of new physics beyond the Standard Model. The recent measurement of the third mixing angle
L. Stanco +4 more
doaj +1 more source
Comptes Rendus. Physique, 2020 A summary of recent precise results in tau and charm physics is presented. Topics include leptonic and hadronic tau decays, lepton flavour and lepton number violation, charm mixing and $\mathit{CP}$ violation, leptonic and semileptonic charm decays, rare
Gersabeck, Evelina, Pich, Antonio
doaj +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
New Physics and the Unitarity Triangle
, 1997 After reviewing the present experimental constraints on the unitarity triangle, I discuss the various ways in which new physics can manifest itself in measurements of the parameters of the unitarity triangle.
London, David
core +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
FEBS Open Bio, EarlyView.UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source