Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
mixtools: An R Package for Analyzing Mixture Models [PDF]
The mixtools package for R provides a set of functions for analyzing a variety of finite mixture models. These functions include both traditional methods, such as EM algorithms for univariate and multivariate normal mixtures, and newer methods that ...
Tatiana Benaglia +3 more
core
Online Quantum Mixture Regression for Trajectory Learning by Demonstration [PDF]
, 2013 16/01/14 MEB. Pre-print version OK to add.In this work, we present the online Quantum Mixture Model (oQMM), which combines the merits of quantum mechanics and stochastic optimization. More specifically it allows for quantum effects on the mixture states,
Dimitrios Korkinof +3 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The D-optimal design of blocked and split-plot experiments with mixture components. [PDF]
So far, the optimal design of blocked and split-plot experiments involving mixture components has received scant attention. In this paper, an easy method to construct efficient blocked mixture experiments in the presence of fixed and/or random blocks is ...
Goos, Peter, Donev, AN
core
Noise adaptive training for subspace Gaussian mixture models [PDF]
, 2013 Noise adaptive training (NAT) is an effective approach to normalise environmental distortions when training a speech recogniser on noise-corrupted speech.
Renals, Steve, Ghoshal, Arnab, Lu, Liang
core
Theoretical principles and experimental data to identify stability of asphalt concrete components in finally dosed mineral materials [PDF]
Transport, 2002 PAPER AVAILABLE IN LITHUANIAN. The duration of asphalt concrete functioning depends on the quality of the asphalt concrete mixture used to pave the road.
H. Sivilevičius
doaj
Zadie Smith’s NW or the art of line-crossing
E-REA, 2014 The purpose of this paper is to examine NW, Zadie Smith’s fourth novel, through the notion of crossings, which can be viewed as ethical connections between characters but also as geographical journeys across London, movements along the social scale ...
Vanessa GUIGNERY
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Assessing the Number of Components in Mixture Models: a Review. [PDF]
Despite the widespread application of finite mixture models, the decision of how many classes are required to adequately represent the data is, according to many authors, an important, but unsolved issue.
Ana Oliveira-Brochado +1 more
core