Results 41 to 50 of about 787,328 (218)

Development of Flash-Calcined Sediment and Blast Furnace Slag Ternary Binders

open access: yesBuildings, 2023
Partial cement replacement by low-carbon-impact additions has the potential to reduce CO2 emissions. The aim of this study is the development of a ternary binder that includes ordinary Portland cement (OPC), ground granulated blast furnace slag (GGBS ...
Ahmed Zeraoui   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Determination of composition of pozzolanic waste mixtures with optimized compressive strength

open access: yesMaterials Research, 2004
The utilization of ceramic wastes with pozzolanic properties along with other compounds for obtaining new materials with cementating properties is an alternative for reducing the environmental pollution. The acceptance of these new products in the market
Nardi José Vidal, Hotza Dachamir
doaj  

Numerical Design and Optimisation of Self-Compacting High Early-Strength Cement-Based Mortars

open access: yesApplied Sciences, 2023
The use of SCC in Europe began in the 1990s and was mainly promoted by the precast industry. Precast companies generally prefer high early-strength concrete mixtures to accelerate their production rate, reducing the demoulding time.
Nara Cangussu   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Unlocking DOE potential by selecting the most appropriate design for rAAV optimization

open access: yesMolecular Therapy: Methods & Clinical Development
Producing recombinant adeno-associated virus (rAAV) for gene therapy via triple transfection is an intricate process involving many cellular interactions.
Konstantina Tzimou   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

In situ misemgel as a multifunctional dual-absorption platform for nasal delivery of raloxifene hydrochloride: formulation, characterization, and in vivo performance

open access: yesInternational Journal of Nanomedicine, 2018
Osama AA Ahmed,1,2 Shaimaa M Badr-Eldin1,3 1Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia; 2Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Minia University, Minia,
Ahmed OAA, Badr-Eldin SM
doaj  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Experimental design and multicriteria decision making methods for the optimization of ice cream composition

open access: yesScientia Agropecuaria, 2012
The aim of the present work was to optimize the sensorial and technological features of ice cream. The experimental work was performed in two stages: 1) optimization of lactose enzymatic hydrolysis, and 2) optimization of the process and product.
Cristian Rojas   +3 more
doaj   +1 more source

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