Results 31 to 40 of about 787,328 (218)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The application of experimental design methodology for the investigation of liquid radioactive waste treatment [PDF]

Nuclear Technology and Radiation Protection, 2017
The sorption properties of waste facade, brick, and asphalt sample towards Sr(II), Co(II), and Ni(II) ions from single and multicomponent solutions were investigated.
Šljivić-Ivanović Marija Z., Jelić Ivana V., Lončar Aleksandra M., Nikezić Dušan P., Dimović Slavko D., Lončar Boris B.   +5 more
doaj   +1 more source

Optimization of Bioactive Phenolics Extraction and Cosmeceutical Activity of Eco-Friendly Polypropylene-Glycol–Lactic-Acid-Based Extracts of Olive Leaf

Molecules, 2022
Olive leaf is a rich source of phenolic compounds with numerous activities related to skin health and appearance. In this study, a green extraction method was developed using eco-friendly solvents: polypropylene glycol (PPG), lactic acid (LA), and water.
Marijan Marijan, Anamarija Mitar, Lejsa Jakupović, Jasna Prlić Kardum, Marijana Zovko Končić   +4 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Optimization of the Rheological Properties of Fat Replacers Based on Inulin at Different Degrees of Polymerization and Their Application in Beef Burgers

Foods
Fats play a key role in the rheological and textural properties of meat products. However, growing awareness of the link between diet and disease has stimulated research on fat replacers that can replicate these functional properties.
Michela Pia Totaro, Mariana Miccolis, Davide De Angelis, Giuseppe Natrella, Francesco Caponio, Carmine Summo, Michele Faccia   +6 more
doaj   +1 more source

Optimization of flexural properties of glass/carbon/durian skin fiber reinforced polymer composites using the mixture design approach

Journal of Applied Science and Engineering, 2023
The objective of this study was to explore the feasibility of employing durian skin fiber (DSF) waste as a reinforcing agent for a composite material composed of glass fiber, carbon fiber and polylactic acid (PLA).
Prayoon Surin, Boonsin Nadondu, Jakawat Deeying   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Lemon-Flavored Gummy Candies: Sourness, Flavor and Overall Acceptance Optimization Using Lattice-Simplex Mixture Design Implemented with Python Programming Language

Biology and Life Sciences Forum
Acidulants enhance the tartness and flavor of gummy candies. This study employed Python, a free, open-source tool, to perform a simplex–lattice mixture design, optimizing the sourness, flavor, and overall acceptance of lemon-flavored gummies.
Jorge Adahir Cruz-Enriquez, Laura García-Curiel, Jesús Guadalupe Pérez-Flores, Elizabeth Contreras-López, Emmanuel Pérez-Escalante, Karla Soto-Vega, Mirandeli Bautista-Ávila, Carlos Ángel-Jijón, Juan Ramírez-Godínez   +8 more
doaj   +1 more source

Blending of Cotton and Poly (lactic Acid) Fiber: Combined Optimization of Blend Ratio and Yarn Twist Using Mixture-Process Design

Journal of Natural Fibers, 2021
Blending of cotton with poly (lactic acid) fiber, regarded as the natural polyester as opposed to the commonly used synthetic polyester, was systematically done by varying the blend ratio and the yarn twist. This was followed by the combined optimization
S. K. Chattopadhyay, R. Guruprasad
doaj   +1 more source