Results 91 to 100 of about 5,779,955 (253)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Asymptotic behaviour of the posterior distribution in overfitted mixture models. [PDF]
In this paper we study the asymptotic behaviour of the posterior distribution in a mixture model when the number of components in the mixture is larger than the true number of components, a situation commonly referred to as overfitted mixture.
Rousseau, Judith, Mengersen, Kerrie
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La Formation sur mesure dans les cégeps en 1986-1987 : état de la situation /
, 1988 La couv.
Québec (Province). Service de formation des adultes +1 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Mixture Models and Convergence Clubs [PDF]
In this paper we argue that modeling the cross-country distribution of per capita income as a mixture distribution provides a natural framework for the detection of convergence clubs.
Pittau, Maria Grazia +2 more
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Journal of Materials Research and TechnologyHigh-entropy (HE) MAX phases represent an emerging family of multi-constituent solid solutions that provide large compositional variations and, therefore, a wide variety of properties. Here, we report the experimental realization of M2AlC (M = Ti/Ta/V/Nb/
Syuzanna Melkonyan +9 more
doaj +1 more source
RESEARCH OF INTERIOR MIXTURE FORMATION IN FOUR-STROKE ENGINE WITH SPARK IGNITION [PDF]
Avtomobilʹnyj Transport (Harʹkov), 2012 The results of analytical research of the processes of film mixing with the direct fuel injection into four-stroke engine cylinder are presented. Duration of the fuel cyclic feed evaporation at the compression stroke was determined.
V. Korogodsky +3 more
doaj
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Noise adaptive training for subspace Gaussian mixture models [PDF]
, 2013 Noise adaptive training (NAT) is an effective approach to normalise environmental distortions when training a speech recogniser on noise-corrupted speech.
Renals, Steve, Ghoshal, Arnab, Lu, Liang
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