Results 101 to 110 of about 5,779,955 (253)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Flexible Rasch Mixture Models with Package psychomix [PDF]

Measurement invariance is an important assumption in the Rasch model and mixture models constitute a flexible way of checking for a violation of this assumption by detecting unobserved heterogeneity in item response data.
Carolin Strobl, Friedrich Leisch, Achim Zeileis, Hannah Frick   +3 more
core  

Formation of Composite Polyaniline and Graphene Oxide by Physical Mixture Method

Journal of Aerospace Technology and Management, 2017
The development of polyaniline and graphene oxide composites aims to join the unique properties of each material for aerospace applications. The present paper demonstrates an easy and quick method, compared to the ones found in the literature, to obtain ...
Ludmila Resende Vargas, Anne Karoline dos Santos Poli, Rita de Cássia Lazzarini Dutra, Camila Brito de Souza, Maurício Ribeiro Baldan, Emerson Sarmento Gonçalves   +5 more
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Determination of Required Energy Action at Formation of Asphalt Concrete Mixture

Известия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2009
A problem pertaining to determination of the concentrated exergy of the asphalt concrete mixture is considered in the paper. The paper shows the possibility to use the concentrated exergy of the asphalt concrete mixture for qualitative energy evaluation ...
B. M. Khroustalev, V. N. Romaniuok
doaj  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Tooth Graft and Platelet‐Rich Fibrin Mixture for Oral Bone Reconstruction and Preservation: A Scoping Review

Clinical and Experimental Dental Research
Aim This scoping review aimed to evaluate effectiveness of using tooth graft (TG) mixture with platelet‐rich fibrin (PRF), examining their roles in oral bone reconstruction and preservation, and evaluating the clinical and histopathological outcomes ...
Mina Shekarian, Fateme Aghajani, Zahra Sadat Mohajer Hejazi, Pedram Iranmanesh, Bahamin Mousa Akbari‐Bezenjani, Abbasali Khademi   +5 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source