Results 131 to 140 of about 791,274 (314)

Estimating propensity scores with missing covariate data using general location mixture models

, 2009
In many observational studies, researchers estimate causal effects using propensity scores, e.g., by matching or sub-classifying on the scores. Estimation of propensity scores is complicated when some values of the covariates aremissing.
Reiter, Jerome P., Jerome P. Reiter, Mitra, Robin, Robin Mitra   +3 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Rcapture: Loglinear Models for Capture-Recapture in R

Journal of Statistical Software, 2007
This article introduces Rcapture, an R package for capture-recapture experiments. The data for analysis consists of the frequencies of the observable capture histories over the t capture occasions of the experiment. A capture history is a vector of zeros
Sophie Baillargeon, Louis-Paul Rivest
doaj  

Composite and Mixture Distributions for Heavy-Tailed Data—An Application to Insurance Claims

Mathematics
This research provides a comprehensive analysis of two-component non-Gaussian composite models and mixture models for insurance claims data. These models have gained attraction in actuarial literature because they provide flexible methods for curve ...
Walena Anesu Marambakuyana, Sandile Charles Shongwe   +1 more
doaj   +1 more source

Prediction with mixture models.

, 2014
Das Lernen eines Modells für den Zusammenhang zwischen den Eingabeattributen und annotierten Zielattributen von Dateninstanzen dient zwei Zwecken. Einerseits ermöglicht es die Vorhersage des Zielattributs für Instanzen ohne Annotation. Andererseits können die Parameter des Modells nützliche Einsichten in die Struktur der Daten liefern.
openaire   +2 more sources

The Standardized Spectroscopic Mixture Model

Remote Sensing
The standardized spectral mixture model combines the specificity of a physically based representation of a spectrally mixed pixel with the generality and portability of a spectral index. Earlier studies have used spectrally and geographically diverse collections of broadband and spectroscopic imagery to show that the reflectance of the majority of ice ...
Christopher Small 0002, Daniel J. Sousa
openaire   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Comparison of single distribution and mixture distribution models for modelling LGD

, 2009
Estimating Recovery Rate and Recovery Amount has taken a more importance in consumer credit because of both the new Basel Accord regulation and the increase in number of defaulters due to the recession.
Thomas, Lyn C., Zhang, Jie
core