Results 141 to 150 of about 8,492,854 (308)
Composite and Mixture Distributions for Heavy-Tailed Data—An Application to Insurance Claims
MathematicsThis research provides a comprehensive analysis of two-component non-Gaussian composite models and mixture models for insurance claims data. These models have gained attraction in actuarial literature because they provide flexible methods for curve ...
Walena Anesu Marambakuyana +1 more
doaj +1 more source
The Standardized Spectroscopic Mixture Model
Remote SensingThe standardized spectral mixture model combines the specificity of a physically based representation of a spectrally mixed pixel with the generality and portability of a spectral index. Earlier studies have used spectrally and geographically diverse collections of broadband and spectroscopic imagery to show that the reflectance of the majority of ice ...
Christopher Small 0002, Daniel J. Sousa
openaire +3 more sources
Asymmetric Multivariate Normal Mixture GARCH [PDF]
An asymmetric multivariate generalization of the recently proposed class of normal mixture GARCH models is developed. Issues of parametrization and estimation are discussed.
Markus Haas +2 more
core
, 2012 Estimating Recovery Rate and Recovery Amount has become important in consumer credit because of the new Basel Accord regulation and because of the increase in number of defaulters due to the recession.
Lyn C. Thomas +3 more
core +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
On the Bayesian analysis of species sampling mixture models for density estimation [PDF]
, 2006 The mixture of normals model has been extensively applied to density estimation problems. This paper proposes an alternative parameterisation that naturally leads to new forms of prior distribution.
Griffin, Jim E.
core
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source