Results 181 to 190 of about 791,274 (314)

The Predictive Performance of Asymmetric Normal Mixture GARCH in Risk Management: Evidence from Turkey [PDF]

open access: yes
The purpose of this study is to test predictive performance of Asymmetric Normal Mixture GARCH (NMAGARCH) and other GARCH models based on Kupiec and Christoffersen tests for Turkish equity market.
Atilla Çifter, Alper Özün
core  

Adaptive Mesh Refinement for Two-Phase Viscoelastic Fluid Mixture Models. [PDF]

open access: yesComput Fluids
Nagda BM   +4 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Estimation methods comparison of SVAR model with the mixture of two normal distributions - Monte Carlo analysis [PDF]

open access: yes
This paper addresses the issue of obtaining maximum likelihood estimates of parameters for structural VAR models with a mixture of distributions. Hence the problem does not have a closed form solution, numerical optimization procedures need to be used. A
Katarzyna Maciejowska
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

The Equity Index Skew, Market Crashes and Asymmetric Normal Mixture GARCH [PDF]

open access: yes
The skewness in physical distributions of equity index returns and the implied volatility skew in the risk-neutral measure are subjects of extensive academic research.
Emese Lazar, Carol Alexandra
core  

Computationally efficient multi-sample flow cytometry data analysis using Gaussian mixture models. [PDF]

open access: yesBMC Bioinformatics
Rutten P   +4 more
europepmc   +1 more source

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