Results 51 to 60 of about 948,008 (290)

Impact of endocrine disrupting chemicals and pharmaceuticals on Sertoli cell development and functions

open access: yesFrontiers in Endocrinology, 2023
Sertoli cells play essential roles in male reproduction, from supporting fetal testis development to nurturing male germ cells from fetal life to adulthood.
Maia Corpuz-Hilsabeck, Martine Culty
doaj   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida   +6 more
wiley   +1 more source

Dose–response relationship between multiple trace elements and risk of all-cause mortality: a prospective cohort study

open access: yesFrontiers in Nutrition, 2023
ObjectivesWe aimed to prospectively investigate the independent and combined relationship between trace elements concentrations [blood (selenium, manganese), serum (copper, zinc), and urine (cobalt, molybdenum, tin, strontium, iodine)] and all-cause ...
Shaohua Zhao   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Ion solvation in aqueous-organic mixtures [PDF]

open access: yes, 2004
The importance of ion solvation in determining the properties of electrolyte solutions in aqueous-organic solvent mixtures is discussed. Solubility measurements are shown to be particularly useful for determining the Gibbs energies of transfer of ions ...
Hefter, G.T., Hefter, G.
core  

Cyclopiazonic Acid Induces Mitochondrial Oxidative Stress in SH-SY5Y Cells: Protective Effects of Extra Virgin Olive Oil Phenolics

open access: yesToxins
Cyclopiazonic acid (CPA), a neurotoxin produced by Penicillium and Aspergillus genera, induces oxidative stress and neuronal damage, mechanisms implicated in neurodegenerative diseases.
Carmen Martínez-Alonso   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Mixtures of Stick-Breaking Processes [PDF]

open access: yes, 2008
We consider mixtures of stickbreaking processes as a generalization of the mixture of Dirichlet process model. We provide a sampling algorithm which covers all such models provide specific reasons for using particular choices of prior.
Walker, Stephen G., Kalli, Maria
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Adsorption Kinetics of Polymer/Surfactant Mixtures at an Expanding Air/Water Interface [PDF]

open access: yes, 2013
The dynamic adsorption mechanisms of a range of polymer/surfactant mixtures have been studied at the expanding air/water interface created by an overflowing cylinder.
ANGUS-SMYTH, ANNA
core  

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