Results 91 to 100 of about 3,621 (204)

Mapping malignant T‐cell states and immune circuits in Sézary syndrome by single‐cell analysis

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Peripheral blood single‐cell RNA‐seq from leukaemic CTCL defined three malignant T‐cell programmes: MTC CM, MTC Reg and MTC E/EM, each with distinct features and candidate vulnerabilities. For example, inferred immune circuits highlighted actionable IL‐10/JAK–TYK2–STAT3 signalling, KIR–MHC I inhibitory interactions and myeloid/B‐cell inflammatory and ...
Beth A. Childs   +6 more
wiley   +1 more source

Durability of response to icotrokinra for high‐impact site psoriasis: 1‐year ICONIC‐TOTAL findings

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Participants with at least moderate scalp, genital or hand/foot psoriasis receiving once‐daily oral icotrokinra achieved high, durable rates of overall and high‐impact site psoriasis clearance, showed substantial nail psoriasis improvement and exhibited no safety signals through 1 year, supporting icotrokinra use for long‐term management of high‐impact
Richard B. Warren   +15 more
wiley   +1 more source

Revolutionising fabrication advances and applications of 3D printing with composite materials: a review

open access: yesVirtual and Physical Prototyping
A detailed analysis of cutting-edge 3D printing technology and composite materials’ transformational potential in numerous industries. These mixes outperform single-substance composites in mechanical, thermal, and electrical properties, aerospace ...
Ibrahim M. Alarifi
doaj   +1 more source

ALCOHOL ELECTRODES IN BEVERAGE MEASUREMENTS

open access: yes, 1994
An alcohol electrode which had been optimized(1) to give an extended linear response to alcohol, eliminate the classical electrochemical interferences of hydrogen peroxide-based electrodes and be pH independent, was used to measure the alcohol ...
Maria J. F. Rebelo   +7 more
core   +1 more source

Towards standardization of tensile testing for strut-based lattices using compensated beam modeling and strain-energy-based optimization

open access: yesMaterials & Design
Lattice structures are increasingly employed in lightweight, high-performance applications, where additive manufacturing allows precise tailoring of their mechanical response. However, tensile testing remains difficult due to complex geometry, anisotropy,
Nikodmose Moges Gebre   +8 more
doaj   +1 more source

Non‐native pink salmon Oncorhynchus gorbuscha carcasses benefit native benthic macroinvertebrates

open access: yesJournal of Fish Biology, EarlyView.
Abstract The invasion of the North Atlantic by pink salmon Oncorhynchus gorbuscha has raised concerns regarding their impact on coastal rivers. Although the influence of marine‐derived nutrients from returning adult O. gorbuscha on rivers in their native range has received much attention, the ecological consequences of invasive O.
Hui Wei   +9 more
wiley   +1 more source

Synthesis and high ranked NLT properties of new sulfonamide-substituted indium phthalocyanines

open access: yes, 2010
The synthesis and characterization of three new indium phthalocyanines bearing eight N-alkyl- or N-arylsulfonamide groups is described. The new compounds are {2,3,9,10,16,17,23,24-octakis[4-(4-methoxyphenylaminosulfonyl] phenoxy]phthalocyaninato}indium ...
CALVETE MJF   +5 more
core   +1 more source

Spatial Regulation of Silicon Accumulation in Peduncle Confers Sheathed Spike in Barley

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Peduncle, the uppermost internode in cereals, connects the stem to the inflorescence and is critical for the transport of water, nutrients and photosynthetic assimilates. While peduncle length associates with plant height and its elongation is primarily regulated by phytohormones, we report a previously unrecognized mechanism involving the ...
Wenxue Wu   +11 more
wiley   +1 more source

Mathematical model of the zebrafish ventricular cardiomyocyte action potential and calcium transient

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This study presents the development and validation of the first biophysically detailed computational model of the zebrafish ventricular action potential (AP). The model is based on a human cardiomyocyte framework and reparameterized using published and newly generated patch‐clamp recordings of zebrafish ionic currents.
Ludovica Cestariolo   +5 more
wiley   +1 more source

Axial halogen ligand effect on photophysics and optical power limiting of some indium naphthalocyanines

open access: yes, 2007
Three axially substituted complexes, 2,3-octa(3,5-di-terf-butylphenoxy)-2, 3-naphthalocyaninato indium chloride (1a), 2,3-octa(3,5-di-tert-butylphenoxy)-2, 3-naphthalocyaninato indium bromide (1b), and 2,3-octa(3,5-ditert-butylphenoxy)- 2,3 ...
DINI, DANILO   +5 more
core   +1 more source

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