Results 101 to 110 of about 2,565 (182)

Recent Advances in the Use of Natural Deep Eutectic Solvents for Natural Product Sample Preparation: Focus on Purification, Characterization, and Sustainability

Journal of Separation Science, Volume 49, Issue 7, July 2026.
ABSTRACT This review examines recent advances in the use of natural deep eutectic solvents (NaDES) for natural product sample preparation, with emphasis on extraction, purification, analytical compatibility, and sustainability. NaDES emerge as versatile, tunable, and biocompatible media that enhance the recovery and stability of diverse phytochemicals ...
Valeria Cedeño‐Fierro, Juan Felipe Grisales‐Mejía, Harlen Gerardo Torres Castañeda, Jose A. Mendiola   +3 more
wiley   +1 more source

Biomarkers of Leucine‐Rich Repeat Kinase 2 (LRRK2) and Lysosomal Dysfunction in Progressive Supranuclear Palsy

Movement Disorders, Volume 41, Issue 7, Page 1740-1749, July 2026.
Abstract Background Common and rare genetic variants in leucine‐rich repeat kinase 2 (LRRK2) have been linked with sporadic and familial Parkinson's disease (PD). Recently, we discovered that common genetic variation near the LRRK2 locus determined survival in progressive supranuclear palsy (PSP).
Louise‐Kristine Nielsen, Joshua L.I. Frost, David P. Vaughan, Raquel Real, Riona Fumi, Marte Theilmann Jensen, Megan Hodgson, Eleanor J. Stafford, Lesley Wu, Olaf Ansorge, Annelies Quaegebeur, Kieren S.J. Allinson, Thomas T. Warner, Zane Jaunmuktane, Anjum Misbahuddin, P. Nigel Leigh, Boyd C.P. Ghosh, Kailash P. Bhatia, Alistair Church, Christopher Kobylecki, Michele T.M. Hu, James B. Rowe, Alan A. Shomo, Danielle L. Graham, Omar S. Mabrouk, Huw R. Morris, Esther M. Sammler, Edwin Jabbari   +27 more
wiley   +1 more source

Seeing Invisible Oligomers: Rethinking α‐Synuclein Pathology Through Proximity Ligation Assay

Movement Disorders, Volume 41, Issue 7, Page 1680-1689, July 2026.
Abstract Parkinson's disease (PD) and multiple system atrophy are defined by α‐synuclein (αSYN)‐positive inclusions – Lewy bodies (LBs) and glial cytoplasmic inclusions – yet mounting evidence indicates that these inclusions represent only a fraction of disease‐relevant pathology.
Hiroaki Sekiya, Nanna Møller Jensen, Dennis W. Dickson, Poul Henning Jensen   +3 more
wiley   +1 more source

Instability of Gas‐Phase‐Assembled Pd–Fe Alloy Nanoparticles Under Ambient Conditions: Pd/FeOx Core–Shell Formation and Magnetic and Hydrogen‐Sensing Consequences

Small Structures, Volume 7, Issue 7, July 2026.
Pd–Fe nanoparticles exhibit Fe segregation that, upon exposure to ambient conditions, leads to the formation of Pd/FeOx core–shell structures. The resulting ultrathin FeOx shells induce glassy magnetic behavior in nanoparticle films. These results demonstrate how intrinsic segregation combined with oxidation governs the structure and magnetic ...
Moisés G. Zarzoza Medina, Raúl López‐Martín, Benito Santos Burgos, Santiago Ceballos, Óscar J. Durá, Irene Morales, Beatrice Muzzi, José F. Marco, Miguel A. Arranz, Panagiotis Grammatikopoulos, Daniel Salazar, Peter S. Normile, José A. De Toro   +12 more
wiley   +1 more source

Long‐term jaguar demography underscores the ecological value of Amazonian floodplains

Journal of Applied Ecology, Volume 63, Issue 7, July 2026.
Our results provide the first estimates of recruitment and apparent survival for Amazonian jaguars, key parameters for guiding conservation. We show that seasonal wetlands—the Amazonian floodplain forest and reported estimates from Pantanal and the Llanos—harbour the highest jaguar densities across the species' range.
Raíssa Sepulvida, Luca Börger, Anelise Montanarin, James D. Forester, Guilherme Costa Alvarenga, Aline Giroux, Diogo Maia Gräbin, Jorge Fernando Saraiva Menezes, Emiliano Ramalho   +8 more
wiley   +1 more source

Optimisation and Scale‐Up of the Heterologous Production of the Antifungal Protein PeAfpA From Penicillium expansum in Stirred‐Tank Bioreactors

Microbial Biotechnology, Volume 19, Issue 7, July 2026.
This work demonstrates the feasibility of scaling up laboratory processes to pilot scale production of antifungal proteins for diverse applications and exemplifies the possibilities that recyclable CRISPR/Cas9 methodology offers for fungal biotechnology.
Stefani de Ovalle, Sandra Garrigues, Jose V. Gimeno‐Alcañiz, Josep V. Mercader, Antonio Abad‐Fuentes, Jose F. Marcos, Paloma Manzanares   +6 more
wiley   +1 more source

Gender and Innovation During a Business Crisis

Gender, Work &Organization, Volume 33, Issue 4, Page 1327-1346, July 2026.
ABSTRACT This research investigates the relational construction of gender and innovation within small and medium enterprises (SMEs) during systemic business crises. Moving beyond essentialist, trait‐based perspectives, this study adopts a processual feminist lens to explore how gendered organizational practices shape innovative capacity during ...
Timothy Kiessling, Jane F. Maley, Sandeep Yadav, Marina Dabić   +3 more
wiley   +1 more source

Mathematical model of the zebrafish ventricular cardiomyocyte action potential and calcium transient

The Journal of Physiology, Volume 604, Issue 13, Page 5391-5420, 1 July 2026.
Abstract figure legend This study presents the development and validation of the first biophysically detailed computational model of the zebrafish ventricular action potential (AP). The model is based on a human cardiomyocyte framework and reparameterized using published and newly generated patch‐clamp recordings of zebrafish ionic currents.
Ludovica Cestariolo, Zachary D. Long, Arie O. Verkerk, Jose M. Ferrero, T. Alexander Quinn, Jose F. Rodriguez Matas   +5 more
wiley   +1 more source

Fiber type specific tibialis anterior muscle atrophy and oxidative capacity reduction is contemporaneous with death of larger lumbar motor neurons in old rats

Physiological Reports, Volume 14, Issue 14, July 2026.
Abstract Age‐associated muscle weakness and atrophy of limb muscles, termed sarcopenia, is a major factor in the morbidity of the elderly. It is becoming increasingly recognized that a substantial contribution to the sarcopenic phenotype arises from motor neuron (MN) death in old age and subsequent muscle denervation.
Kathryn D. Rooker, Genesis A. Hernandez‐Vizcarrondo, Sang Won Cheung, Sanjana Mahadev Bhat, Alyssa D. Brown, Gary C. Sieck, Matthew J. Fogarty   +6 more
wiley   +1 more source

Flavouring Group Evaluation 216 Revision 3 (FGE.216Rev3): Consideration of the genotoxic potential of α,β‐unsaturated 2‐phenyl‐2‐alkenals from subgroup 3.3 of FGE.19

EFSA Journal, Volume 24, Issue 7, July 2026.
Abstract The EFSA Panel on Food Additives and Flavourings (FAF) evaluated the genotoxic potential of two flavouring substances, 2‐phenylcrotonaldehyde [FL‐no: 05.062] and 5‐methyl‐2‐phenylhex‐2‐enal [FL‐no: 05.099] from subgroup 3.3 of FGE.19, in the Flavouring Group Evaluation 216 revision 3 (FGE.216Rev3).
EFSA Panel on Food Additives and Flavourings (FAF), Laurence Castle, Monica Andreassen, Gabriele Aquilina, Maria Bastos, Polly Boon, Biagio Fallico, Rex FitzGerald, María José Frutos Fernández, Bettina Grasl‐Kraupp, Ursula Gundert‐Remy, Rainer Gürtler, Eric Houdeau, Marcin Kurek, Henriqueta Louro, Patricia Morales, Sabina Passamonti, Claudia Bolognesi, Eugenia Cordelli, Gisela Degen, Karl‐Heinz Engel, Maria Carfí, Alessandra Tosato, Carla Martino   +23 more
wiley   +1 more source