Results 21 to 30 of about 272 (113)

Beyond stroke therapy, neuroaid (a chinese herbal) has an effect on cognition and neurogenesis, a bibliometric study [version 2; peer review: 2 approved] [PDF]

F1000Research
Introduction NeuroAiD, also known as MLC601 or MLC901, is a Chinese herbal combination used worldwide for stroke treatment. It contains herbal components and five hewan components.
Dwi Arwandi Yogi Saputra, Tirta Darmawan Susanto, ARMAN YURISALDI SALEH, Riezky Valentina   +3 more
doaj   +2 more sources

Efficacy and safety of CDP-choline, cerebrolysin, MLC601, and edaravone in recovery of patients with acute ischemic strokes: a meta-analysis

Exploration of Neuroprotective Therapy, 2023
Aim: Stroke is the second most common cause of mortality and disability worldwide with ischemic strokes being the predominant type. The advent of neuroprotectants brought hope of improved outcomes and quality of life, but current guidelines, despite ...
Shafiq Dexter B. Abou Zaki, Johnny K. Lokin   +1 more
doaj   +2 more sources

Phase II randomised, double-blind, placebo-controlled trial to assess the efficacy and safety of MLC1501 in patients with stroke: the MLC1501 study Assessing Efficacy in post-STrOke Subjects with mOtor deficits (MAESTOSO) study protocol [PDF]

Stroke and Vascular Neurology
Background MLC1501, consisting of four herbs, that is, Radix Astragali, Radix Angelicae sinensis, Rhizoma Chuanxiong, Radix Polygalae, has the same pharmacological properties as its precursors MLC601 and MLC901 which contain extracts of nine herbs and ...
Narayanaswamy Venketasubramanian, Deidre Anne De Silva, Christopher P L H Chen, Cyrus G Escabillas, John Harold Hiyadan, Johnny K Lokin, Romulo U Esagunde, Joel M Advincula, Christian Oliver C Co, Maria Epifania V Collantes, Annabelle Y Lao, Yeow-Hoay Koh, Carol Huilian Tham   +12 more
doaj   +2 more sources

A Systematic Search and Review of Registered Pharmacological Therapies Investigated to Improve Outcomes after a Stroke. [PDF]

Cerebrovasc Dis Extra
Introduction: Stroke burden is largely due to long-term impairments requiring prolonged care and loss of productivity. We aim to identify and assess studies of different registered pharmacological therapies as treatments for improving post-stroke ...
Lee TH, Uchiyama S, Kusuma Y, Chiu HC, Navarro JC, Tan KS, Pandian JD, Guo L, Wong Y, Venketasubramanian N, Asian Stroke Advisory Panel.   +10 more
europepmc   +3 more sources

A scoping review of stroke services within the Philippines. [PDF]

BMC Health Serv Res
Background: Stroke is a leading cause of mortality and disability. In higher-income countries, mortality and disability have been reduced with advances in stroke care and early access to rehabilitation services.
Logan A, Faeldon L, Kent B, Ong A, Marsden J.   +4 more
europepmc   +3 more sources

Baseline Characteristics and Treatment Response of Patients from the Philippines in the CHIMES Study [PDF]

International Journal of Stroke, 2014
Background The CHIMES Study compared MLC601 with placebo in patients with ischemic stroke of intermediate severity in the preceding 72 h. Sites from the Philippines randomized 504 of 1099 (46%) patients in the study.
Jose C Navarro, Chun Fan Lee, Christopher Chen   +2 more
exaly   +3 more sources

Novel Insight into the Modulatory Effect of Traditional Chinese Medicine on Cerebral Ischemia-Reperfusion Injury by Targeting Gut Microbiota: A Review. [PDF]

Drug Des Devel Ther
Yisong Ren, Gang Chen, Ying Hong, Qianying Wang, Bo Lan, Zhaozhao Huang Department of Critical Care Medicine, Chengdu Pidu District Hospital of Traditional Chinese Medicine, Chengdu, Sichuan Province, 611731, People’s Republic of ChinaCorrespondence ...
Ren Y, Chen G, Hong Y, Wang Q, Lan B, Huang Z.   +5 more
europepmc   +3 more sources

Spinal cord injury – assessing tolerability and use of combined rehabilitation and NeuroAiD (SATURN) study – primary results of an exploratory study [PDF]

Journal of Spinal Cord Medicine, 2023
Ramesh Kumar, Ohnmar Htwe, Azmi Baharudin   +2 more
exaly   +2 more sources

Safety Profile of MLC601 (Neuroaid®) in Acute Ischemic Stroke Patients: A Singaporean Substudy of the Chinese Medicine Neuroaid Efficacy on Stroke Recovery Study

Cerebrovascular Diseases, 2010
<i>Background:</i> Previous clinical trials have shown that Neuroaid® (MLC601), a traditional Chinese medicine, shows good tolerability and superiority over another traditional Chinese medicine in terms of neurological disability and ...
Angeline Koh, Bernard P.L. Chan, Christopher Chen, Hui Meng Chang, N. Venketasubramanian, Rajinder Singh, Sherry H.Y. Young, Yudong Zhao   +7 more
core   +3 more sources

NeuroAiD® (MLC601) and Amyloid Precursor Protein Processing [PDF]

Cerebrovascular Diseases, 2013
<b><i>Background:</i></b> Amyloid precursor protein (APP) undergoes cleavage under physiological conditions, predominantly by α- and &#947;-secretases, to form the nonpathogenic sAPPα and p3 fragments. By contrast, amyloid-beta (Aβ) is produced via proteolytic cleavage by β- and &#947;-secretases. In Alzheimer's disease (
Lim, YA, Murray, LA, Lai, MKP, Chen, C
openaire   +2 more sources