Results 51 to 60 of about 6,744 (203)

Cannabis‐Based Oil for Pain and Other Non‐Motor Symptoms in Parkinson's Disease: A Randomized Controlled Trial

open access: yesMovement Disorders, EarlyView.
Abstract Background There is a lack of treatments for non‐motor symptoms (NMS) in Parkinson's disease (PD). Objective To assess the safety and effectiveness of an oral Cannabis sativa L. extract on pain and other NMS of PD. Methods This phase II, randomized, placebo‐controlled trial evaluated a formulation containing cannabidiol (CBD; 96 mg/ml) and Δ9 ...
Gabriel T. Kubota   +14 more
wiley   +1 more source

Human Umbilical Cord Mesenchymal Stem Cell‐Derived Microvesicles Alleviate Bronchopulmonary Dysplasia in Preterm Rats by Inhibiting Neutrophil Extracellular Trap Formation

open access: yesPediatric Discovery, EarlyView.
Excessive neutrophil extracellular trap (NET) extrusion (NETosis) links prenatal inflammation to bronchopulmonary dysplasia (BPD) pathogenesis. Treatment with human umbilical cord mesenchymal stem cell‐derived microvesicles suppresses NET formation, reduces lung injury, and promotes alveolarization in a preterm rat model, offering a promising cell‐free
Yi Lu   +10 more
wiley   +1 more source

Noradrenaline depresses facial stimulation-evoked cerebellar MLI-PC synaptic transmission via α2-AR/PKA signaling cascade in vivo in mice

open access: yesScientific Reports, 2023
The noradrenergic fibers of the locus coeruleus, together with mossy fibers and climbing fibers, comprise the three types of cerebellar afferents that modulate the cerebellar neuronal circuit.
Jun-Ya Wang   +6 more
doaj   +1 more source

Artificial intelligence, equity, and pediatric neurodevelopmental disorders: A scoping review of clinical practice applications

open access: yesPediatric Investigation, EarlyView.
Artificial intelligence (AI) is being explored to support diagnosis and care for pediatric neurodevelopmental disorders, yet most tools remain in early stages of development. This scoping review identifies limited external validation, narrow population representation, and sparse equity considerations, underscoring the need for inclusive, clinically ...
Florida Uzoaru   +3 more
wiley   +1 more source

Key Technical Fields and Future Outlooks of Space Manipulators: A Survey

open access: yesSmartBot, EarlyView.
This paper systematically reviews the technological development of space manipulators, emphasizing the unique challenges posed by space environments. It examines four areas: structural design, modeling, planning, and control, while introducing typical ground test platforms.
Gang Chen   +12 more
wiley   +1 more source

A comprehensive review of multi-level inverters, modulation, and control for grid-interfaced solar PV systems

open access: yesScientific Reports
With the significant development in photovoltaic (PV) systems, focus has been placed on inexpensive, efficient, and innovative power converter solutions, leading to a high diversity within power converters and new system configurations for grid-connected
Bhupender Sharma   +5 more
doaj   +1 more source

Field evaluations of thermal optics and tracking tunnels for small mammal surveys at airports and grass dominated habitats

open access: yesWildlife Society Bulletin, EarlyView.
Small mammal survey tools are needed at airports to help inform aircraft strike‐risk management. We evaluated thermal optics and tracking tunnels as small mammal survey tools. We conclude that thermal optics would not be a viable survey tool for mouse‐sized mammals (19‐41 g) at airfields and other thick grass habitats unless grass height was maintained
Aaron B. Shiels   +4 more
wiley   +1 more source

Quantitative lung morphology: semi-automated measurement of mean linear intercept

open access: yesBMC Pulmonary Medicine, 2019
Background Quantifying morphologic changes is critical to our understanding of the pathophysiology of the lung. Mean linear intercept (MLI) measures are important in the assessment of clinically relevant pathology, such as emphysema. However, qualitative
George Crowley   +8 more
doaj   +1 more source

Nicotine pouches and clinical outcomes related to smoking cessation: A systematic review of randomized trials

open access: yesAddiction, EarlyView.
Abstract Background and aims Tobacco‐free nicotine pouches (NPs) are oral nicotine products promoted by manufacturers and some researchers as tools that may reduce nicotine cravings and support smoking reduction or cessation. However, evidence regarding their actual clinical impact remains limited.
Javad Heshmati   +6 more
wiley   +1 more source

Prevalence and risk perceptions of nicotine pouch use: A systematic review of population‐based studies

open access: yesAddiction, EarlyView.
Abstract Background and Aims Oral nicotine pouches (NPs) are a new class of non‐combustible nicotine products that have gained rapid popularity. Despite rising sales and marketing, evidence of their prevalence and risk perceptions remains limited. This systematic review aimed to synthesize the available global evidence on the prevalence and patterns of
Salma Mahmoodianfard   +7 more
wiley   +1 more source

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