Results 221 to 230 of about 11,198,539 (258)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Quantifying the contribution of modifiable risk factors for progression of MGUS to multiple myeloma in a Veteran population. [PDF]

Int J Cancer
Wang M, Sigel B, Liu L, Huber JH, Ji M, Schoen MW, Sanfilippo KM, Thomas TS, Colditz GA, Hsu SH, Wang SY, Chang SH.   +11 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Integrating interferon gamma receptor pathways, antigenicity, and immune contexture as predictors of immunotherapeutic strategies for mucosal melanomas. [PDF]

J Immunother Cancer
Monti M, Picinoli S, Bozzola A, Ferrari M, Bugatti M, Pezzali I, Carlomagno M, Carta G, Orlandi M, Lora G, Benerini Gatta L, Missale F, Ferrari G, Baldazzi V, Rezzola S, Tabellini G, Parolini S, Manfredi M, De Giorgis V, Marengo E, Turri-Zanoni M, Nicolai P, Consoli F, Lombardi D, Martini P, Li J, Griffith O, Griffith M, Rossato M, Vermi W.   +29 more
europepmc   +1 more source

Differences in characteristic morphological variability among distal femurs based on sex and ethnicity. [PDF]

Bone Jt Open
Ammoury N, Dunbar MJ, D'Alessio J, Astephen Wilson J.   +3 more
europepmc   +1 more source

Is Accurate Dental Implant Placement Feasible Using a Novel Dynamic Computer-Assisted Surgery System Without Patient Optical Markers or Registration? A Preliminary Retrospective Cohort Study. [PDF]

Clin Exp Dent Res
He G, Liao H, Sheng H, Valmaseda-Castellón E, Figueiredo R.   +4 more
europepmc   +1 more source

Sustainable bioconversion of excess grape must into polyhydroxyalkanoates by Cupriavidus necator DSM 545 and Hydrogenophaga pseudoflava DSM 1034. [PDF]

Bioresour Bioprocess
Caminiti V, Gupte AP, Casella S, Lucchetta M, Favaro L, Basaglia M.   +5 more
europepmc   +1 more source

Pathway selection between click and acyl transfer reactions driven by aminoacyl phosphates. [PDF]

Nat Commun
Bhattacharjee D, Sharma A, Dai K, Pramod T, Saile L, Thomann R, Pappas CG.   +6 more
europepmc   +1 more source