Results 91 to 100 of about 11,212,458 (259)
Energy of a knot: variational principles; Mm-energy [PDF]
Let $E_f$ be the energy of some knot $\tau$ for any $f$ from certain class of functions. The problem is to find knots with extremal values of energy. We discuss the notion of the locally perturbed knot.
Karpenkov, O. N.
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Conceptual modelling and the quality of ontologies: A comparison between object-role modelling and the object paradigm [PDF]
Ontologies are key enablers for sharing precise and machine-understandable semantics among different applications and parties. Yet, for ontologies to meet these expectations, their quality must be of a good standard.
Al-Asswad, MM +3 more
core
MM Algorithms for Minimizing Nonsmoothly Penalized Objective Functions
In this paper, we propose a general class of algorithms for optimizing an extensive variety of nonsmoothly penalized objective functions that satisfy certain regularity conditions.
Schifano, Elizabeth D. +2 more
core +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Numerical Full wave Analysis and Modeling of Plasmonic HEMT Performance Using Hydrodynamic Model
The two dimensional (2D) plasmon propagation in the channel of a high electron mobility transistor (HEMT) is numerically modeled using the full wave technique.
Farzaneh Daneshmandian +2 more
doaj
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Behaviour of composite floor slabs under fire conditions [PDF]
This paper is concerned with the ultimate behaviour of composite floor slabs during fire scenarios. Steel/concrete composite structures are increasingly common in the UK and worldwide, particularly for multi-storey construction.
Cashell, KA, Florides, MM
core
Sub-mm observations and modelling of Vega type stars
We present new sub-mm observations and modelling of Vega excess stars, using realistic dust grain models. For resolved disks, we find that different objects require very different dust grain properties in order to simultaneously fit the image data and ...
Augereau +67 more
core +3 more sources
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source

