High-Efficiency, 80 mm Aperture Metalens Telescope. [PDF]
Metalenses promise potential for a paradigm shift of conventional optical devices. However, the aperture sizes of metalenses are usually bound within hundreds of micrometers by the commonly used fabrication methods, limiting their usage on practical ...
Lidan Zhang +7 more
semanticscholar +1 more source
Optimal Design of Active Multiple Tuned Mass Dampers (AMTMDs) For Nonlinear Hysteretic Structures [PDF]
In this paper optimal design and effectiveness assessment of active multiple tuned mass dampers (AMTMDs) in reducing the vibration of nonlinear hysteretic structures has been studied.
Mohtasham Mohebbi, Hosein Shabani
doaj +1 more source
FREE VIBRATION ANALYSIS OF CRACKED POST-BUCKLED BEAM BY DIFFERENTIAL QUADRATURE METHOD [PDF]
The vibration analysis of cracked post-buckled beam is investigated using the differential quadrature method. Crack, assumed to be open, is modeled by a massless rotational spring.
P. Jamshidi Moghadam, S. Moradi
doaj +1 more source
Prevalence of Extended Spectrum Beta-lactamase and Carbapenemase Producers in Gram Negative Bacteria causing Blood Stream Infection in Intensive Care Unit Patients [PDF]
Introduction: Blood Stream Infections (BSI) in Intensive Care Unit (ICU) patients at initial stages are acute infections which might even become life threatening.
Narinder Kaur +7 more
doaj +1 more source
The MM/PBSA and MM/GBSA methods to estimate ligand-binding affinities
Introduction: The molecular mechanics energies combined with the Poisson–Boltzmann or generalized Born and surface area continuum solvation (MM/PBSA and MM/GBSA) methods are popular approaches to estimate the free energy of the binding of small ligands ...
S. Genheden, U. Ryde
semanticscholar +1 more source
What is the current value of MM/PBSA and MM/GBSA methods in drug discovery?
The computer-aided drug design field is constituted by a wide range of different approaches that can be roughly classified as either ligandor receptor-based techniques.
T. Tuccinardi
semanticscholar +1 more source
Insights on prospects of nano-siRNA based approaches in treatment of Cancer
siRNA interference, commonly referred to as gene silence, is a biological mechanism that inhibits gene expression in disorders such as cancer. It may enhance the precision, efficacy, and stability of medicines, especially genetic therapies to some extent.
Rajat Goyal +5 more
doaj +1 more source
Streptomyces olivaceus ATCC 31365 produces a family of novel beta-lactam antibiotics collectively referred to as the olivanic acids. Seven such compounds, MM 4550, MM 13902, MM 17880, MM 22380, MM 22381, MM 22382 and MM 22383 have been identified which have the same carbapenem nucleus but with different side chains attached to the nucleus.
M J, Basker, R J, Boon, P A, Hunter
openaire +3 more sources
Secondary Hemophagocytic Lymphohistiocytosis with Severe Dengue: A Rare but Dreadful Complication [PDF]
Hemophagocytic lymphohistiocytosis (HLH) is a devastating and rare multisystemic disorder characterized by an autoimmune phenomenon leading to reactive hyperactivity of cytotoxic T cells and histiocytes mediated by cytokine storm.
Ashwani K Sood +3 more
doaj +1 more source
With an alarming increase in the number of cancer patients and a variety of tumors, it is high time for intensive investigation on more efficient and potent anti-tumor agents.
Upala Dasmahapatra +8 more
semanticscholar +1 more source

