Results 1 to 10 of about 4,797 (179)

A myeloid-dormant metabolic transcriptome identifies a poor-prognosis subgroup in hyperdiploid multiple myeloma with targetable vulnerabilities [PDF]

Blood Cancer Journal
Aberrant metabolism, a hallmark of cancer, reveals vulnerabilities across human tumors. Here, we demonstrate that transcriptomic alterations of metabolism-related genes (metabolic transcriptome) in multiple myeloma (MM), classify patients into six ...
Naroa Barrena, Edurne San José-Enériz, Luis V. Valcárcel, Danel Olaverri-Mendizabal, Estibaliz Urizar-Compains, Leire Garate, Estíbaliz Miranda, Paula Rodriguez-Marquez, Romika Kumari, Patxi San Martín-Uriz, Juan Roberto Rodriguez-Madoz, Leonor Puchades-Carrasco, Caroline A. Heckman, Paula Rodriguez-Otero, Francisco J. Planes, Xabier Agirre, Felipe Prósper   +16 more
doaj   +2 more sources

Downslope windstorm in Iceland – WRF/MM5 model comparison [PDF]

Atmospheric Chemistry and Physics, 2011
A severe windstorm downstream of Mt. Öræfajökull in Southeast Iceland is simulated on a grid of 1 km horizontal resolution by using the PSU/NCAR MM5 model and the Advanced Research WRF model.
Ó. Rögnvaldsson, J.-W. Bao, H. Ágústsson, H. Ólafsson   +3 more
doaj   +7 more sources

Comprehensive genomic profiling of mucosal melanoma reveals novel fusion transcripts and dysregulation of cell-cycle, MAPK, and PI3K pathways. [PDF]

J Pathol
Abstract Mucosal melanomas (MMs) are rare, aggressive cancers with poor outcomes and limited response to standard therapies. A significant knowledge gap exists regarding their genomic landscape and corresponding druggable targets. This study explores this issue through a multi‐omic analysis, including whole exome‐, RNA‐, and targeted sequencing, of ...
Monti M, Romanello MB, Agnelli L, Orlandi M, Bertoli L, Picinoli S, Pezzali I, Mandelli GE, Medicina D, Ribaudo G, Busico A, Conca E, Pellegrini V, Balzarini P, Gallucci D, Di Matteo A, Lombardi D, Ghigna C, Pruneri G, Gianoncelli A, Rossato M, Vermi W.   +21 more
europepmc   +2 more sources

Bottlebrush Polyolefin Sulfones as Triggerable and Degradable Pressure-Sensitive Adhesives. [PDF]

Angew Chem Int Ed Engl
A grafting‐through alternating copolymerization strategy yields poly(norbornene sulfone) bottlebrush polymers with high molar mass. These materials function as additive‐free pressure‐sensitive adhesives. The incorporation of cleavable sulfone units enables rapid breakdown under mild alkaline conditions, providing a pathway toward sustainable, high ...
Vu C, Addo ID, Ham W, Choudhury U, Worch JC, Matson JB.   +5 more
europepmc   +3 more sources

MM5 simulations of a SCOS97-NARSTO episode [PDF]

Atmospheric Environment, 2003
Abstract MM5 simulations of the 4–7 August SCOS97-NARSTO ozone episode in the SoCAB showed that a relatively rare easterly upper-level background flow influenced surface wind flow directions at in-land sites. An inland-moving surface convergence zone resulted where the offshore background flow met an inland moving westerly (sea breeze plus thermal ...
R Bornstein
exaly   +4 more sources

ارزیابی الگوریتم SPA و امکان‌سنجی استفاده از برو‌نداد مدل MM5 برای تخمین داده‌های مفقود ناشی از ابر‌ناکی در تصاویرLST مودیس [PDF]

جغرافیا و مخاطرات محیطی, 2019
روش‌های اندکی به امکان‌سنجی استفاده از برونداد مدل‌های پیش‌بینی عددی در تخمین مقادیر از دست‌رفته تصاویر سنجش‌ازدور پرداخته‌اند. بدین منظور در تحقیق حاضر علاوه بر ارزیابی الگوریتم SPA در بازسازی تصاویر، امکان‌ استفاده از برونداد مدل پیش‌بینی عددی MM5 در ...
نگار سیابی, سید حسین ثنایی نژاد, بیژن قهرمان   +2 more
doaj   +1 more source

The impact of MM5 and WRF meteorology over complex terrain on CHIMERE model calculations [PDF]

Atmospheric Chemistry and Physics, 2009
The objective of this study is to evaluate the impact of meteorological input data on calculated gas and aerosol concentrations. We use two different meteorological models (MM5 and WRF) together with the chemistry transport model CHIMERE. We focus on the
A. de Meij, A. Gzella, C. Cuvelier, P. Thunis, B. Bessagnet, J. F. Vinuesa, L. Menut, H. M. Kelder   +7 more
doaj   +1 more source

2-way coupling the hydrological land surface model PROMET with the regional climate model MM5 [PDF]

Hydrology and Earth System Sciences, 2013
Most land surface hydrological models (LSHMs) consider land surface processes (e.g. soil–plant–atmosphere interactions, lateral water flows, snow and ice) in a spatially detailed manner.
F. Zabel, W. Mauser
doaj   +1 more source

Comparison of Urban Canopy Schemes and Surface Layer Schemes in the Simulation of a Heatwave in the Xiongan New Area

Atmosphere, 2022
Due to rapid growth and expansion, Xiongan New Area is at risk for heatwaves in the present and future induced by the urban heat island effect. Based on eight combined schemes, including two common WRF surface layer schemes (MM5 and Eta) and urban canopy
Yiguo Xu, Wanquan Gao, Junhong Fan, Zengbao Zhao, Hui Zhang, Hongqing Ma, Zhichao Wang, Yan Li, Lei Yu   +8 more
doaj   +1 more source

Predictive ability of severe rainfall events over Catalonia for the year 2008 [PDF]

Natural Hazards and Earth System Sciences, 2011
This paper analyses the predictive ability of quantitative precipitation forecasts (QPF) and the so-called "poor-man" rainfall probabilistic forecasts (RPF).
A. Comellas, L. Molini, A. Parodi, A. Sairouni, M. C. Llasat, F. Siccardi   +5 more
doaj   +1 more source