Results 141 to 150 of about 34,846 (226)

Slow Transit Constipation: Pathophysiological Perspectives and Management Updates

open access: yesJournal of Digestive Diseases, EarlyView.
Slow transit constipation (STC) is a complex neuromuscular disorder driven by interstitial cells of Cajal (ICCs) loss and enteric neuropathy. Diagnosis relies on objective transit testing while excluding pelvic floor dysfunction. Management follows a stepwise, phenotype‐driven approach, progressing from conventional laxatives to emerging targeted ...
Athanasios Syllaios   +8 more
wiley   +1 more source

Lithography-free subwavelength metacoatings for high thermal radiation background camouflage empowered by deep neural network. [PDF]

open access: yesNanophotonics
Qiu Q   +10 more
europepmc   +1 more source

Development of a novel risk score reflecting the relative harm potential of synthetic cannabinoids based on prevalence estimates, well‐documented intoxication cases and basic pharmacological data

open access: yesAddiction, EarlyView.
Abstract Background and aims While the health hazards of synthetic cannabinoid receptor agonists (SCRAs) are often approximated using in vitro pharmacological parameters as surrogate, this approach fails to consider pharmacokinetic and pharmacodynamic complexity.
Michaela J. Sommer   +3 more
wiley   +1 more source

Mitomycin C-induced DNA double-strand breaks are enhanced by catalytical inactivation of DNA polymerase κ in mice. [PDF]

open access: yesGenes Environ
Wada NA   +16 more
europepmc   +1 more source

Dose‐Dependent Effects of Simulated Clinical Radiotherapy on the Structure and Properties of Root Dentine

open access: yesAustralian Endodontic Journal, EarlyView.
ABSTRACT Head and neck radiotherapy (HNRT) can expose teeth to moderate radiation doses, yet the effects on root dentine under clinically relevant conditions remain unclear. This in vitro study compared dentine subjected to 0, 30, or 50 Gy IMRT. Palatal roots from 35 maxillary molars were allocated to non‐irradiated, 30 Gy (oropharyngeal simulation ...
Anna Victória Costa Serique   +11 more
wiley   +1 more source

Submucosal Mitomycin C Injection in the Endoscopic Treatment of Laryngotracheal Stenosis: Experience of a Tertiary Center. [PDF]

open access: yesJ Clin Med
Russo E   +8 more
europepmc   +1 more source

Characterisation of the Mesial Root and Middle Mesial Canal Morphology in Mandibular First Molars: An Ex Vivo Micro‐CT Study

open access: yesAustralian Endodontic Journal, EarlyView.
ABSTRACT This ex vivo study characterised the mesial root morphology of mandibular first molars with a middle mesial canal (MMC) using micro‐CT. Among 469 scanned molars, 42 (8.96%) presented an MMC. Morphological parameters analysed included canal configuration, chamber orifice features, dentine thickness, isthmus type, and aspect ratio.
Nuno Rodrigues dos Santos   +3 more
wiley   +1 more source

Clinical outcomes of the PAUL glaucoma implant in primary open‐angle and pseudoexfoliative glaucoma eyes after failed glaucoma surgeries

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose This study assesses the PAUL® glaucoma implant (PGI) in primary open angle glaucoma (POAG) and pseudoexfoliative glaucoma (PEXG) after failed glaucoma surgery. Given PEXG's more aggressive nature, limited research exists on PGI outcomes in this subgroup. This study aims to compare PGI's efficacy and safety in both conditions. Methods A
Constance Liegl   +8 more
wiley   +1 more source

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