Results 171 to 180 of about 88,142 (297)

Human Epidermal Growth Factor Receptor 2-Positive, Claudin-18 Isoform 2-Positive, Mismatch Repair-Deficient Gastric Cancer Revealed by Immunohistochemical Analysis of Surgical Specimens: A Case Report. [PDF]

Cancer Rep (Hoboken)
Takagi D, Mori M, Shuto K, Kosugi C, Usui A, Takayanagi R, Sato S, Adachi S, Fujino T, Yamazaki K, Shimizu H.   +10 more
europepmc   +1 more source

BRD9 inhibition as potential treatment option for testicular germ cell tumors

Andrology, EarlyView.
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen, Christine Sanders, Florian Fronhoffs, Kai Funke, Glen Kristiansen, Hubert Schorle   +5 more
wiley   +1 more source

Pharmacologic Inhibition of PMS2 Induces MMR Deficiency and Response to Immune Checkpoint Blockade. [PDF]

Cancer Discov
Blagg J, Riou P, Hervieu A, Piumatti E, Rodriguez-Plata MT, Battuello P, Peall A, Amodio V, Vitiello PP, Nightingale DJH, Bago R, Tongue P, Slater T, Parmar K, Patel P, Rodríguez González J, Clark DE, Langley GW, Nichols C, Guarné A, Winship PCM, Baker M, Drysdale M, Germano G, Bardelli A.   +24 more
europepmc   +1 more source

Broader Familial Cancer Risk in Relatives of Testicular Cancer Patients: Insights From Two Mediterranean Populations

Andrology, EarlyView.
ABSTRACT Background Familial clustering of testicular germ cell tumour (TGCT) is well‐established, whereas the risk of non‐testicular cancer among relatives remains inconsistent across studies. Objective To evaluate the overall and site‐specific cancer risk among first‐degree relatives and grandparents of TGCT patients compared to cancer‐free controls.
Csilla Krausz, Chiara Abrardo, Viktoria Rosta, Daniel Moreno‐Mendoza, Luca Bressan, Matteo Vannucci, Rebecca Passerotti, Arianna Meacci, Ginevra Farnetani, Viola Bonini, Giovanni Corona, Maria Grazia Fino, Eduard Ruiz‐Castañé, Antoni Riera‐Escamilla   +13 more
wiley   +1 more source

A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics

Andrology, EarlyView.
ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis, Lisa Schneider, Felix Bremmer, Daniel Nettersheim   +3 more
wiley   +1 more source

Trends in maternal mortality in China and Hainan Province: an analysis based on GBD 2023 and Hainan surveillance data. [PDF]

Front Glob Womens Health
Chen R, Li X, Wu G, Gong H.
europepmc   +1 more source

[Retracted] Aberrant expression of miR‑130a‑3p in ankylosing spondylitis and its role in regulating T‑cell survival. [PDF]

Mol Med Rep
Li F, Si D, Guo X, Guo N, Li D, Zhang L, Jian X, Ma J.   +7 more
europepmc   +1 more source

Ethical Considerations Regarding the Vaccination of Children—The Power Dynamics Between Doctors and Parents

Acta Paediatrica, EarlyView.
ABSTRACT While childhood vaccination programmes provide outstanding contributions to improving health, they can also pose challenges through the interactions between parents and healthcare. This paper focuses on the ethical dimensions of interactions between healthcare professionals and parents. Since the knowledge that professionals possess creates an
Mikael Sandlund, Ingemar Engström, Anders Castor   +2 more
wiley   +1 more source

Molecular characterization of mismatch repair deficient tumors in young Jordanian patients. [PDF]

Discov Oncol
Ahmad O, Sultan I, Hussaini M, Alsmadi O, Sutter C, Hirsch S, Autry RJ, Previti C, Försti A, Schwalm B, AbuJamous L, Amayiri N, Shanap MA, Amareen R, Aljawabrah S, Fryjat L, Al-Naimat A, Qaisi A, Alnaimat H, Reuss DE, Fernandez NR, Das A, Tabori U, Pfister SM, Schaaf CP.   +24 more
europepmc   +1 more source

Modelling Impact of Different Varicella Immunisation Strategies Upon Introduction in the Swedish National Programme

Acta Paediatrica, EarlyView.
ABSTRACT Aim Countries with varicella immunisation programmes have seen major reductions in disease burden. While two‐dose schedules are now universally adopted, dosing ages vary, and some countries initially include catch‐up vaccination of older children to speed impact. This modelling study assessed three two‐dose schedules in the Swedish setting (1)
Gianpaolo Scalia Tomba, Frida Kasteng, Annika Ersson, Sören Andersson, Emma Appelqvist, Marie Nordahl, Kari Johansen   +6 more
wiley   +1 more source