Results 51 to 60 of about 152,985 (282)

Benchmarking of force fields to characterize the intrinsically disordered R2-FUS-LC region

Scientific Reports, 2023
Intrinsically Disordered Proteins (IDPs) play crucial roles in numerous diseases like Alzheimer's and ALS by forming irreversible amyloid fibrils. The effectiveness of force fields (FFs) developed for globular proteins and their modified versions for ...
Maud Chan-Yao-Chong, Justin Chan, Hidetoshi Kono   +2 more
doaj   +1 more source

Mirror Movements in Acquired Neurological Disorders: A Mini-Review

Frontiers in Neurology, 2021
Mirror movements (MMs) are specifically defined as involuntary movements occurring on one side of homologous muscles when performing unilateral movements with the contralateral limb.
Ping Liu, Yuan Yuan, Ning Zhang, Xiaoyan Liu, Lihua Yu, Benyan Luo   +5 more
doaj   +1 more source

The Small-Scale Physical Structure and Fragmentation Difference of Two Embedded Intermediate Mass Protostars in Orion [PDF]

, 2012
Intermediate-mass (IM) protostars, the bridge between the very common solar-like protostars and the more massive, but rarer, O and B stars, can only be studied at high physical spatial resolutions in a handful of clouds.
A. Fuente, Adams, Adams, Andrews, Arce, Bate, Bergin, Beuther, Beuther, Boss, Boss, Bottinelli, Brogan, Bruderer, Carrasco-González, Chambers, Cyganowski, D. Johnstone, De Buizer, Di Francesco, Dunham, Enoch, Evans, Gutermuth, Johnstone, Johnstone, Jørgensen, Klessen, Krumholz, Krumholz, Kuiper, Longmore, McKee, Ossenkopf, Pon, Ragan, Robitaille, Robitaille, S. N. Longmore, Sadavoy, Schnee, Seth, Shinnaga, Shirley, Shirley, Skinner, Stanke, Stojimirović, T. A. van Kempen, T. Pillai, Torrelles, Trinidad, Vorobyov, Vorobyov, Vázquez-Semadeni, Zavagno   +55 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

CHECKING THE FUNCTIONALITY OF A NETWORK ON DATA EXCHANGE BETWEEN THE DEVICES ON THE DIGITAL SUBSTATION

Вестник Северо-Кавказского федерального университета, 2022
Around the world, much attention is paid to the new communication technology IEC 61850. A special place is occupied by the program of Digitization of the electric grid complex of the Russian Federation, according to which 40 digital substations will ...
Daria Tuchina, Aleksey Starchenko, Tatyan Strebkova, Julia Pitko   +3 more
doaj  

Methyl methanesulfonate (MMS) produces heat-labile DNA damage but no detectable in vivo DNA double-strand breaks [PDF]

, 2005
Homologous recombination (HR) deficient cells are sensitive to methyl methanesulfonate (MMS). HR is usually involved in the repair of DNA double-strand breaks (DSBs) in Saccharomyces cerevisiae implying that MMS somehow induces DSBs in vivo. Indeed there
Erixon, K., Goldman, A.S.H., Helleday, T., Jenssen, D., Lundin, C., North, M., Walters, K.   +6 more
core   +2 more sources

Homolog of Saccharomyces cerevisiae SLX4 is required for cell recovery from MMS-induced DNA damage in Candida albicans [PDF]

, 2021
Yueqing Wang, Na Wang, Jia Liu, Yaxuan Zhang, Xiaojiaoyang Li, Qi Han   +5 more
openalex   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Preparation of magnetic mesoporous silica from rice husk for aflatoxin B1 removal: Optimum process and adsorption mechanism

PLoS ONE, 2020
The liquid foodstuffs such as edible oil products remain a problem of excessive aflatoxin B1 (AFB1) content. This paper focused on the preparation of magnetic mesoporous silica (MMS) from rice husk ash for the removal of AFB1 in oil system.
Yanan Li, Ren Wang, Zhengxing Chen, Xiuping Zhao, Xiaohu Luo, Li Wang, Yongfu Li, Fei Teng, Mohammad A. Al-Ghouti   +8 more
doaj   +2 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source