Results 61 to 70 of about 55,884 (291)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Imaged continuum and spectral line cubes for L1451-MMS (L1451MMS, L1451 MMS, L1451 ...
Stephens, Ian
core +2 more sources
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Supplemental material, sj-pdf-1-mms-10.1177_10812865211057211 for Crack nucleation at forging flaws studied by non-local peridynamics simulations by Mohammad Rezaul Karim, Kai Kadau, Santosh Narasimhachary, Francesco Radaelli, Christian Amann, Kaushik ...
Christian Amann (11854903) +7 more
core +1 more source
a mm is a mm - the architect as an organizer
This is a story about a detail in a system. This is a story about a detail and a city. The greater Reykjavik area is taking a step away from the domination of the private car. The century of mixed transportation has arrived: bicycles, busses, scooters, even with walking, have become a thing in Iceland.
openaire +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Architecture de systèmes dans l'environnement MMS
"Manufacturing Message Specification" (MMS) is an OSI application layer protocol that allows remote applications (called clients) to control and supervise various heterogeneous industrial devices (called servers).
Castori, Pierre
core +1 more source
Benchmarking of force fields to characterize the intrinsically disordered R2-FUS-LC region
Intrinsically Disordered Proteins (IDPs) play crucial roles in numerous diseases like Alzheimer's and ALS by forming irreversible amyloid fibrils. The effectiveness of force fields (FFs) developed for globular proteins and their modified versions for ...
Maud Chan-Yao-Chong +2 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The impact of a microplastic (MP) mixture composed of polyethylene (PE) and polypropylene (PP) plastic particles, prepared from commercially available products, was evaluated in blue mussels Mytilus spp.
Messika Revel +11 more
doaj +1 more source

