Results 1 to 10 of about 2,159 (166)

Associations of Multimarkers of Metabolic Malnutrition and Inflammation With All‐Cause Mortality and Their Interplay With Thyroid Function [PDF]

Endocrinology, Diabetes & Metabolism
Introduction The metabolic vulnerability index (MVX)—a composite biomarker reflecting metabolic malnutrition and inflammation—has been linked to increased mortality risk in populations with cardiovascular disease.
Setor K. Kunutsor, Reyhaneh Rikhtehgaran, Yanning Xu, Margery A. Connelly, Irina Shalaurova, Layal Chaker, Stephan J. L. Bakker, Robin P. F. Dullaart   +7 more
doaj   +3 more sources

MMX® technology and its applications in gastrointestinal diseases [PDF]

Therapeutic Advances in Gastroenterology, 2017
The Multimatrix ® (MMX ® ) preparation MMX ® is a recently obtained drug formulation developed to facilitate release of high concentrations of active drugs into the colon, with a homogeneous distribution along all colonic segments, particularly the most ...
Luca Pastorelli, Silvia Nardelli, Gian Eugenio Tontini   +2 more
exaly   +4 more sources

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation. [PDF]

Adv Sci (Weinh)
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Abbott K, Hardo G, Li R, Bradley J, Zarkan A, Bakshi S.   +5 more
europepmc   +3 more sources

Short-Term Risk Stratification in Alcohol-Associated Hepatitis: Small HDL Particles and Inflammation Vulnerability Index Values Improve Model for End-Stage Liver Disease. [PDF]

Alcohol Clin Exp Res (Hoboken)
Lower small HDL particles (S‐HDL‐P), the key component of the Inflammation Vulnerability Index, were associated with greater alcohol‐associated hepatitis (AH) severity and higher 90‐day AH‐related mortality. S‐HDL‐P improved Model for End‐Stage Liver Disease (MELD)‐based prognostic model fit, while IVX (inflammation vulnerability index) provided ...
Vilar-Gomez E, Connelly MA, Shah VH, Shalaurova I, Rafalko JM, Sanyal AJ, Chalasani NP, Gawrieh S, TREAT Consortium.   +8 more
europepmc   +2 more sources

Increased failure of budesonide MMX for ulcerative colitis during the COVID-19 pandemic: a population-based study [PDF]

Therapeutic Advances in Gastroenterology
Background: Corticosteroids induce remission in ulcerative colitis (UC) but are associated with adverse effects, including prednisone ⩾20 mg/day associated with serious COVID-19 outcomes.
Stephanie Coward, Karen J. B. Martins, Scott Klarenbach, Lawrence P. Richer, Christopher Ma, Remo Panaccione, Cynthia H. Seow, Karen Kroeker, Frank Hoentjen, Laura E. Targownik, Gilaad G. Kaplan   +10 more
doaj   +2 more sources

Association of metabolic and inflammation vulnerabilities with systemic lupus erythematosus: a prospective UK Biobank study [PDF]

Frontiers in Immunology
BackgroundSystemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease influenced by complex metabolic and inflammatory pathways, but the impact of specific metabolic and inflammatory signatures, particularly metabolic vulnerability index ...
Dongqi Zhou, Lisha Sun, Na Li, Yi Liang, Gaofeng Gan, Dazhou Liao, Qiu Chen   +6 more
doaj   +2 more sources

MIRS: an imaging spectrometer for the MMX mission [PDF]

Earth, Planets and Space, 2021
The MMX infrared spectrometer (MIRS) is an imaging spectrometer onboard MMX JAXA mission. MMX (Martian Moon eXploration) is scheduled to be launched in 2024 with sample return to Earth in 2029.
Maria Antonietta Barucci, Jean-Michel Reess, Pernelle Bernardi, Alain Doressoundiram, Sonia Fornasier, Michel Le Du, Takahiro Iwata, Hiromu Nakagawa, Tomoki Nakamura, Yves André, Shohei Aoki, Takehiko Arai, Elisa Baldit, Pierre Beck, Jean-Tristan Buey, Elisabet Canalias, Matthieu Castelnau, Sebastien Charnoz, Marc Chaussidon, Fréderic Chapron, Valerie Ciarletti, Marco Delbo, Bruno Dubois, Stephane Gauffre, Thomas Gautier, Hidenori Genda, Rafik Hassen-Khodja, Gilles Hervet, Ryuki Hyodo, Christian Imbert, Takeshi Imamura, Laurent Jorda, Shingo Kameda, Driss Kouach, Toru Kouyama, Takeshi Kuroda, Hiroyuki Kurokawa, Laurent Lapaw, Jeremie Lasue, Laetitia Le Deit, Aurélien Ledot, Cedric Leyrat, Bertrand Le Ruyet, Moe Matsuoka, Frederic Merlin, Hideaki Miyamoto, Frederic Moynier, Napoleon Nguyen Tuong, Kazunori Ogohara, Takahito Osawa, Jérôme Parisot, Laurie Pistre, Benjamin Quertier, Sean N. Raymond, Francis Rocard, Takeshi Sakanoi, Takao M. Sato, Eric Sawyer, Fériel Tache, Sylvain Trémolières, Fuminori Tsuchiya, Pierre Vernazza, Didier Zeganadin   +62 more
doaj   +4 more sources

Evidence of immune-metabolic imbalance prior to sepsis: a prospective study in the UK Biobank [PDF]

Frontiers in Nutrition
BackgroundSepsis is a severe systemic inflammatory response syndrome, and effective metabolic signatures for predicting its risk are currently lacking.
Xiaoke Liu, Dongqi Zhou, Dazhou Liao, Qiu Chen   +3 more
doaj   +2 more sources

Budesonide MMX in the Treatment of Ulcerative Colitis: Current Perspectives on Efficacy and Safety

Therapeutics and Clinical Risk Management, 2021
Giovanni Maconi, Deborah Camatta, Rosanna Cannatelli, Francesca Ferretti, Anna Carvalhas Gabrielli, Sandro Ardizzone Gastroenterology Unit, Department of Biomedical and Clinical Sciences FBF – L.Sacco, University Hospital, Milan ...
Sandro Ardizzone, Francesca Ferretti, Giovanni Maconi   +2 more
exaly   +2 more sources

Real-World Adherence and Relapse Risk in Mesalamine Treatment for Ulcerative Colitis: Insights from a Large Japanese Medical Claims Database [PDF]

Inflammatory Intestinal Diseases
Introduction: 5-Aminosalicylic acid (5-ASA, mesalamine) is the cornerstone for maintaining remission in mild-to-moderate ulcerative colitis (UC), with several formulations available.
Takafumi Wada, Shuhei Hosomi, Yumie Kobayashi, Rieko Nakata, Yu Nishida, Hirotsugu Maruyama, Masaki Ominami, Yuji Nadatani, Shusei Fukunaga, Koji Otani, Fumio Tanaka, Yasuhiro Fujiwara   +11 more
doaj   +2 more sources