Results 211 to 220 of about 126,389 (308)

Carbohydrate‐Based Drug Discovery: Synthetic Strategies and Clinical Applications

Israel Journal of Chemistry, Volume 66, Issue 3, May 2026.
The picture depicts the molecules discussed in the review. On the left side, the general scaffold of sugars is shown. Next to it are four carbohydrate‐based molecules, including remdesivir, islatravir, empagliflozin, and Globo‐H. Remdesivir and islatravir contain a substituted ribose ring attached to a modified nucleobase.
Stephan Scheeff, Jemma Arakelyan, Billy Wai‐Lung Ng   +2 more
wiley   +1 more source

Considerations for establishing occupational exposure limits for small molecule kinase inhibitors in drug development. [PDF]

Front Toxicol
Nicholas T, Morinello E, Moudgal C, Beaulieu A, Graham J.   +4 more
europepmc   +1 more source

Limitations of Subgroup Safety Analyses for Drug–Drug Interaction Evaluation: Insights from the Talazoparib P‐gp Inhibitor Case

The Journal of Clinical Pharmacology, Volume 66, Issue 5, May 2026.
Abstract Impact of concomitant medications (conmeds) on the safety of the investigational agent is often evaluated using subgroup analyses for safety events in patients who received the conmed versus those who did not. Here, we highlight the potential biases and inconclusive results that can arise from such analyses, using talazoparib and P ...
Diane Wang, Charvi Nanavati, Derek Z. Yang, Liza DeAnnuntis, Mohamed Elmeliegy   +4 more
wiley   +1 more source

A 3D-Printed Transoral Guide Device to Aid Single-Person Fiberoptic Intubation: A Randomized Clinical Trial. [PDF]

Med Sci Monit
Wu T, Dong M, Sui H, Chen W, Wang Y, Chen Y.   +5 more
europepmc   +1 more source

Registration of high‐yielding conventional soybean ‘R18‐14502’ with broad adaptability in the U.S. Mid‐South

Journal of Plant Registrations, Volume 20, Issue 2, May/August 2026.
Abstract ‘R18‐14502’ (Reg. no. CV‐566, PI 706684) is a conventional maturity group Late‐IV (Relative maturity 4.8) soybean [Glycine max (L.) Merr.] variety developed and released by the University of Arkansas System—Division of Agriculture Research & Extension Center in 2023.
C. Canella Vieira, R. G. Marmo, A. L. Tischler, L. Florez‐Palacios, C. Wu, A. Acuña, D. Harrison, D. Rogers, J. F. Carlin   +8 more
wiley   +1 more source

Artificial intelligence drives the identification and screening of novel antibiotics and antimicrobial peptides. [PDF]

Brief Bioinform
Zhou Q, Sun L, Ou Y, Liu H, Gao J, Dai R, Li Y, Cheng G, Tao Y, Pan Y, Huang L.   +10 more
europepmc   +1 more source

Potential of Beauveria bassiana in the control of Euschistus crenator (Hemiptera: Pentatomidae) and selectivity to the parasitoid Telenomus podisi (Hymenoptera: Scelionidae)

Pest Management Science, Volume 82, Issue 5, Page 5015-5025, May 2026.
Entomopathogenic fungi effectively suppressed the emerging soybean pest Euschistus crenator, with isolates LCMAP106, UFSM‐01 and a commercial bioinsecticide achieving the highest mortality. These agents did not reduce parasitism or survival of the egg parasitoid Telenomus podisi, highlighting their potential for integration into environmentally ...
Paulo Henrique Martins da Silva, Gustavo Andrade Carneiro, Ricardo Antonio Polanczyk   +2 more
wiley   +1 more source

Confounder-aware foundation modeling for accurate phenotype profiling in cell imaging. [PDF]

Npj Imaging
Papanastasiou G, Sanchez PP, Christodoulidis A, Yang G, Pinaya WHL.   +4 more
europepmc   +1 more source

Pharmacokinetics, Pharmacodynamics, Efficacy and Drug Resistance Selection of Injectable Long‐Acting Lenacapavir Pre‐Exposure Prophylaxis (PrEP) Against HIV

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 5, May 2026.
ABSTRACT Oral pre‐exposure prophylaxis (PrEP) can substantially reduce HIV infection risk when taken as prescribed. However, many individuals struggle adhering to the daily regimen. Twice‐yearly injections of the novel HIV capsid inhibitor lenacapavir (LEN) demonstrated potential in recent PrEP trials.
Hee‐yeong Kim, Antonia Liebenberg, Lanxin Zhang, Max von Kleist   +3 more
wiley   +1 more source

A custom-made appliance for mandibular mobilization in children with limited mouth opening. [PDF]

J Oral Biol Craniofac Res
Maleki M, Elshennawy S, Haghighi P, Masnyi T, Stevens K.   +4 more
europepmc   +1 more source