Results 21 to 30 of about 58,944 (350)
Proteomic method to extract, concentrate, digest and enrich peptides from fossils with coloured (humic) substances for mass spectrometry analyses [PDF]
Royal Society Open Science, 2019 Humic substances are breakdown products of decaying organic matter that co-extract with proteins from fossils. These substances are difficult to separate from proteins in solution and interfere with analyses of fossil proteomes.
Elena R. Schroeter +3 more
doaj +1 more source
Journal of Enzyme Inhibition and Medicinal Chemistry, 2022 Herein, we report the preparation of a panel of Schiff bases analogues as antiprotozoal agents by modification of the stereoelectronic effects of the substituents on N-1 and N-4 and the nature of the chalcogen atom (S, Se). These compounds were evaluated
Alexandra Ibáñez-Escribano +13 more
doaj +1 more source
Computational analyses of mechanism of action (MoA): data, methods and integration
RSC Chemical Biology, 2021 The elucidation of a compound's Mechanism of Action (MoA) is a challenging task in the drug discovery process, but it is important in order to rationalise phenotypic findings and to anticipate potential side-effects. Bioinformatic approaches, advances in
Maria-Anna Trapotsi +2 more
semanticscholar +1 more source
Proceedings of the Royal Society of London. Series B: Biological Sciences, 2004 Until a few hundred years ago, New Zealand hosted several species of flightless ratite birds, collectively known as the moa. We have used mitochondrial sequence data for Dinornis, the largest of the moa, and new coalescent approaches to estimate its population size prior to human arrival ca. 1000-6000 years BP. We show that, as little as 1000 years ago,
Neil J, Gemmell +2 more
openaire +2 more sources
Behavior Research Methods, 2021 Performance in everyday tasks, such as driving and sport, requires allocation of attention to task-relevant information and the ability to inhibit task-irrelevant information.
A. Mackenzie +7 more
semanticscholar +1 more source
Treatment of inflammatory bowel disease from the immunological perspective
Immunological Medicine, 2020 Since 1950, the number of patients with inflammatory bowel disease (IBD) in Japan has been increasing. Recent research data indicate that the pathophysiology of IBD involves abnormalities in disease susceptibility genes, environmental factors and ...
Hiroshi Nakase
doaj +1 more source
MOA-seq identifies shared and unique regions in open chromatin.
, 2021 Comparison of MOA-seq to open chromatin profiling techniques DNS-Seq and ATAC-Seq. (A) Genome-wide distribution of MOA-seq footprints relative to genomic annotations. (B) MOA-seq read coverage (CPM) is non-randomly distributed around genes.
Daniel L. Vera (3175611) +10 more
core +1 more source
The Exoplanet Mass-Ratio Function from the MOA-II Survey: Discovery of a Break and Likely Peak at a Neptune Mass [PDF]
, 2016 We report the results of the statistical analysis of planetary signals discovered in MOA-II microlensing survey alert system events from 2007 to 2012.
D. Suzuki +28 more
semanticscholar +2 more sources
High-resolution coproecology: using coprolites to reconstruct the habits and habitats of New Zealand's extinct upland Moa (Megalapteryx didinus) [PDF]
, 2012 Knowledge about the diet and ecology of extinct herbivores has important implications for understanding the evolution of plant defence structures, establishing the influences of herbivory on past plant community structure and composition, and identifying
Wilmshurst, J. +34 more
core +1 more source
MoA: Mixture-of-Attention for Subject-Context Disentanglement in Personalized Image Generation [PDF]
ACM SIGGRAPH Conference and Exhibition on Computer Graphics and Interactive Techniques in AsiaWe introduce a new architecture for personalization of text-to-image diffusion models, coined Mixture-of-Attention (MoA). Inspired by the Mixture-of-Experts mechanism utilized in large language models (LLMs), MoA distributes the generation workload ...
Kuan-Chieh Jackson Wang +4 more
semanticscholar +1 more source