Results 71 to 80 of about 13,467 (261)
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao +5 more
wiley +1 more source
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He +10 more
wiley +1 more source
Sustainable Materials Design With Multi‐Modal Artificial Intelligence
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu +8 more
wiley +1 more source
Welcome message from the Editor-in-Chief and Co-Editor-in-Chief
Xiaohua Jia, Hua Wang
doaj +3 more sources
Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li +4 more
wiley +1 more source
The quest for security in mobile ad hoc networks
So far, research on mobile ad hoc networks has been focused primarily on routing issues. Security, on the other hand, has been given a lower priority. This paper provides an overview of security problems for mobile ad hoc networks, distinguishing the threats on basic mechanisms and on security mechanisms.
Hubaux, Jean-Pierre +2 more
openaire +2 more sources
Interpretable machine learning reveals how composition and processing govern the formation and microstructural burden of Fe‐rich intermetallic compounds in recycled Al–Si–Fe–Mn alloys. By separating morphology selection from morphology‐conditioned burden partitioning, this framework shows that identical Fe contents can yield different intermetallic ...
Jaemin Wang +2 more
wiley +1 more source
Study of the relationship between mobility model of ad hoc network and its connectivity
Three of ad hoc mobility models were introduced,and a formula to calculate the connectivity of mobile ad hoc network was proposed.These mobility models were simulated in NS2,and the relationship among the number of nodes,the range of nodes and the ...
ZHAO Jian-li1 +3 more
doaj +2 more sources
Efficient Cluster Head Selection Algorithm for MANET
In mobile ad hoc network (MANET) cluster head selection is considered a gigantic challenge. In wireless sensor network LEACH protocol can be used to select cluster head on the bases of energy, but it is still a dispute in mobil ad hoc networks and ...
Khalid Hussain +4 more
doaj +1 more source
A DLN dataset was built to analyze MABS composition versus in vitro/in vivo osteogenesis and angiogenesis. An MLP neural network, taking BG morphological parameters as input, extracts bioactive features from these datasets. A rabbit tibial defect model then validates 4D‐printed MABS for adaptability and bone regeneration in critical defects.
Xiongjie Liang +12 more
wiley +1 more source

