Results 41 to 50 of about 167,841 (261)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Improving Podcast Distribution on Gwanda using PrivHab: a Multiagent Secure Georouting Protocol.
Advances in Distributed Computing and Artificial Intelligence Journal, 2015 We present PrivHab, a multiagent secure georouting protocol that improves podcast distribution on Gwanda, Zimbabwe. PrivHab learns the whereabouts of the nodes of the network to select an itinerary for each agent carrying a piece of data.
Adrián SÁNCHEZ-CARMONA +2 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
A Distributed and Collaborative Intelligent System for Medical Diagnosis
Advances in Distributed Computing and Artificial Intelligence Journal, 2013 In this paper, we present a distributed collaborative system assisting physicians in diagnosis when processing medical images. This is a Web-based solution since the different participants and resources are on various sites.
Naoufel KHAYATI, Wided LEJOUAD-CHAARI
doaj +1 more source
, 2002 For years to come, we can predict an important increase in the use of software systems using mobile code. Those systems give birth to new development problems compared to current distributed systems. In particular, testing for such systems must take into account the mobility of tested processes, which makes it difficult to maintain contact points ...
Mikael Marche +2 more
openaire +1 more source
A mobile agent infrastructure for the mobility support [PDF]
Proceedings of the 2000 ACM symposium on Applied computing - Volume 2, 2000 The mobility of terminals and users is a crucial issue in the open global system represented by the Internet. Supporting terminal and user mobility requires a middleware infrastructure capable of efficiently answering the needs of scalable resource discovery, of security and interoperability, of Quality of Service (QoS) monitoring and adaptation.
Paolo Bellavista +2 more
openaire +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Novel mobile agent dynamic data integrity protection protocol
Tongxin xuebao, 2007 Integrity characteristics of dynamic data was redefined and classified by attacker capability,and then it was analyzed how to protect truncation attack with collusion.After that,a data protection protocol of free-roaming agent was presented.The protocol ...
LI Peng-fei1 +3 more
doaj
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source