Results 41 to 50 of about 184,867 (310)

Probabilistic Model of Random Encounter in Obstacle Space

open access: yesISPRS International Journal of Geo-Information, 2019
Based on probabilistic time-geography, the encounter between two moving objects is random. The quantitative analysis of the probability of encounter needs to consider the actual geographical environment.
Zhang-Cai Yin   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Mobile Agents Approach for Transaction Processing in Mobile Database Systems – Mobile Learning Environment [PDF]

open access: yesAAOU Journal, 2011
This paper describes the architecture of using the Mobile Agent and ACID (Atomicity, Consistency, Isolation and Durability) in Mobile e-Learning (mLearning).
Sheng-Hung Chung, Ean-Teng Khor
doaj   +1 more source

Task Automation Intelligent Agents: A Review

open access: yesFuture Internet, 2023
As technological advancements increase exponentially, mobile phones become smarter with machine learning and artificial intelligence algorithms. These advancements have allowed mobile phone users to perform most of their daily routine tasks on mobile ...
Abdul Wali   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Mobile Agents for Mobile Tourists: A User Evaluation of Gulliver's Genie [PDF]

open access: yes, 2005
How mobile computing applications and services may be best designed, implemented and deployed remains the subject of much research. One alternative approach to developing software for mobile users that is receiving increasing attention from the research ...
O'Hare, G.M.P., Sas, Corina, O'Grady, M.
core  

Service fusion in mobile contexts

open access: yes, 2010
Service provision for mobile users poses several challenges for those managing enterprise information systems. Some of these are ubiquitous, for example, privacy and security. Others give rise to integration and interoperability issues.
Michael J. O’Grady   +7 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

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